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Valeriana fauriei Briq. - Valerianaceae
직 ì 오 줌 풀 Jui-o-zoom-pool (Korean), Faurie’s valerian, Korean valerian, Japanese valerian, Japanischer Baldrian
Erect perennial herb, 40-80cm tall; native to the mountains of Japan and Korea; basal leaves small; leaves on the stem pinnate, with 5-7 leaflets; flowers with pink corolla, 5-7mm long, stamen longer then the corolla-tube.
The strong-smelling root is traditionally used as antispasmodic and sedative.
[ Medicinal Plants in the Republic of Korea World Health Organisation, Manila ISBN 92 9061 120 0 (1998)]
„Antidepressant activity-guided fractionation of the MeOH extract of Valeriana fauriei Briq. roots resulted in the isolation of two new germacrane-type sesquiterpenes (1–2) in addition to seven known ones (3–9). Their structures were elucidated as 1β,10α-dihydroxyl-8α-acetoxyl-10β,11,11-trimethyl-4-formyl-bicyclogermacren-E-4(5)-ene (1), 1β-hydroxyl-8α-acetoxyl-11,11-dimethyl-4-formyl-bicyclogermacren-E-4(5),10(14)-diene (2), bicyclo[8,1,0]5β-hydroxyl-7β-1acetoxyl-5α,11,11′-trimethyl -E-1(10)-ene-4α,15-olide (3), 8α-acetoxyl-3α,4α,10-trihydroxyl-guaia-1(2)-ene-12,6α-olide (4), 2-Ethylhexyl-4-hydroxybenzoate (5), 11αH-gemacra-1(10)E,4Z-diene-3-one-12,6α-olide (6), β-Sitoterol (7), isovaleric acid (8), isoborneol acetate (9), using a combination of UV, IR, mass spectroscopy, 1D and 2D NMR spectroscopy. The antidepressant activity of compounds 1–4 was investigated by the FST on mice. Among them, compounds 3 and 4 showed the significant antidepressant activity (*, P < 0.01).“
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