Valeriana fauriei Briq. - Valerianaceae
직 ì 오 줌 풀 Jui-o-zoom-pool (Korean), Faurie’s valerian, Korean valerian, Japanese valerian, Japanischer Baldrian
Erect perennial herb, 40-80cm tall; native to the mountains of Japan and Korea; basal leaves small; leaves on the stem pinnate, with 5-7 leaflets; flowers with pink corolla, 5-7mm long, stamen longer then the corolla-tube.
The strong-smelling root is traditionally used as antispasmodic and sedative.
[ Medicinal Plants in the Republic of Korea World Health Organisation, Manila ISBN 92 9061 120 0 (1998)]
„Antidepressant activity-guided fractionation of the MeOH extract of Valeriana fauriei Briq. roots resulted in the isolation of two new germacrane-type sesquiterpenes (1–2) in addition to seven known ones (3–9). Their structures were elucidated as 1β,10α-dihydroxyl-8α-acetoxyl-10β,11,11-trimethyl-4-formyl-bicyclogermacren-E-4(5)-ene (1), 1β-hydroxyl-8α-acetoxyl-11,11-dimethyl-4-formyl-bicyclogermacren-E-4(5),10(14)-diene (2), bicyclo[8,1,0]5β-hydroxyl-7β-1acetoxyl-5α,11,11′-trimethyl -E-1(10)-ene-4α,15-olide (3), 8α-acetoxyl-3α,4α,10-trihydroxyl-guaia-1(2)-ene-12,6α-olide (4), 2-Ethylhexyl-4-hydroxybenzoate (5), 11αH-gemacra-1(10)E,4Z-diene-3-one-12,6α-olide (6), β-Sitoterol (7), isovaleric acid (8), isoborneol acetate (9), using a combination of UV, IR, mass spectroscopy, 1D and 2D NMR spectroscopy. The antidepressant activity of compounds 1–4 was investigated by the FST on mice. Among them, compounds 3 and 4 showed the significant antidepressant activity (*, P < 0.01).“
[In vivo antidepressant activity of sesquiterpenes from the roots of Valeriana fauriei Briq., Liu, X. G., Gao, P. Y., Wang, G. S., Song, S. J., Li, L. Z., Li, X., Zhang, Z. X., Fitoterapia, Vol.83(3), 2012, 599-603]