Rhamnus cathartica L. - Rhamnaceae - common buckthorn, purging buckthorn, European buckthorn, Purgier-Kreuzdorn, Echter Kreuzdorn

Deciduous shrub, 1-3m high, native to Europe, Sibiria, naturalized in northwestern Africa, North America; twig-ends spiny; bark grey when young, later brown; leaves mostly opposite, ovate, shiny; flowers small, yellow-green; berries green when young, mature ones black.

„The bark and fruit were used as a purgative in the past, though their potentially dangerous violent action and side effects means they are now rarely used.“

Dried berries (Rhamni cathartici fructus) are used as stimulant laxative. Actice constituents are anthranoids of the emodin type (1,8-dihydroxyanthracene derivatives) as glycosides, which are broken down into anthrones when they reach the colon. „Molecular targets include a chloride channel and less importantly the Na,K-ATPase. Anthrones enhance the secretion of water and inhibit its resorption in the colon, so that liquefied stool and a gentle laxative effect is obtained.“
[Medicinal Plants of the World. Ben-Erik Van Wyk and Michael Wink, Pretoria 2004, 267]


rhamnus_cathartica_l.txt · Zuletzt geändert: 2015/06/13 11:40 (Externe Bearbeitung)