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--- fumaria_officinalis_l [2015/10/04 13:22]
andreas
+++ fumaria_officinalis_l [2016/05/01 13:38] (aktuell)
andreas
@@ Zeile 3: / Zeile 3: @@
 Annual herb, up to 80cm tall, native to Europe, Southwest Asia, naturalized elsewhere (Northern America); leaves blueish green, deeply dissected; flowers characteristic, purplish pink or white near base, deep reddish purple to maroon apically. [[http://efloras.org/florataxon.aspx?flora_id=1&taxon_id=220005380]]
-Total alkaloid content in F.offinalis aerial parts was found 1386 mg/100g d.w. (138.6?)with main components fumarophycine (19-37 mg/100g dw), O-methyl fumarophycine (17-29 mg/100g dw), and [[https://en.wikipedia.org/wiki/Protopine|protopine]] (17-22 mg/100g dw). Total phenolics content in F.officinalis was 2600-2900 mg/100g dw. (?) [[https://de.wikipedia.org/wiki/Fumars%C3%A4ure|Fumaric acid]] was found in all of 8 Fumaria species. \\
+Total alkaloid content in F.offinalis aerial parts was found 1386 mg/100g d.w. (138.6?) with main components fumarophycine (19-37 mg/100g dw), O-methyl fumarophycine (17-29 mg/100g dw), and [[https://en.wikipedia.org/wiki/Protopine|protopine]] (17-22 mg/100g dw). Total phenolics content in F.officinalis was 2600-2900 mg/100g dw. (?) [[https://de.wikipedia.org/wiki/Fumars%C3%A4ure|Fumaric acid]] was found in all of 8 Fumaria species. \\
 [Alkaloids and organic acids content of eight Fumaria species., Soušek, J., Guedon, D., Adam, T., Bochořáková, H., Taborska, E., Valka, I., Šimánek, V., Phytochemical Analysis, 10(1), 1999, 6-11]
 {{:fumarophycine.jpg| fumarophycine}} \\ fumarophycine
 (Structure of Fumarophycine., Castillo, M., Saunders, J.K., MacLean, D.B., Mollov, N.M., Yakimov, G.I., Canadian Journal of Chemistry, 49(1), 1971, 139-142)
+Protopine exhibited the known papaverine-like musculotropic (antispasmodic) action. Electric field stimulated contractions of isolated ileum of guinea-pig were antagonized by protopine more than by coptisine and chelidonine. \\
+[Antispasmodic and relaxant activity of chelidonine, protopine, coptisine, and Chelidonium majus extracts on isolated guinea-pig ileum., Hiller, K.O., Ghorbani, M., Schilcher, H., Planta medica, 64(8), 1998, 758-760]
 The herb is traditionally used as cholagogue and spasmolytic to treat biliary and dyspeptic disorders. It is also used as diuretic and laxative, and externally to treat psoriasis and chronic eczema. "In common with other members of the poppy family, fumitory herb contains several alkaloids (1%): protoberberine (scoulerine) and protopine (= fumarin, the main alkohol), also spirobenzylisoquinoline (fumaricine, fumariline) and indenbenzazepines (fumaritine, fumarofine) alkaloids... The alkaloids have sedative and spasmolytic properties." \\
 [Medicinal Plants of the World. Ben-Erik Van Wyk and Michael Wink, Pretoria 2004, 148]
-Uusing ethanol 50% (w/w) at a temperature of 79 °C with a 3% solid–liquid (w/w) ratio, the weight of protopine extracted from 100 g of F. officinalis was about 230 mg. \\
+Uusing ethanol 50% (w/w) at a temperature of 79 °C with a 3% solid-liquid (w/w) ratio, the weight of protopine extracted from 100 g of F. officinalis was about 230 mg. \\
 [Solid-liquid extraction of protopine from Fumaria officinalis L. - Experimental study and process optimization., Rakotondramasy-Rabesiaka, L., Havet, J.L., Porte, C., Fauduet, H., Separation and Purification Technology, 59(3), 2008, 253-261]
@@ Zeile 21: / Zeile 24: @@
 Dietrich, A.G., Flora regni borussici, vol.5 t.348 (1837) \\
 [[http://plantgenera.org/species.php?id_species=446862]]
+{{:fumaria_officinalis_phtoto.jpg?800}}

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