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cnidium_officinale_mak [2015/06/12 23:09]
andreas |
cnidium_officinale_mak [2015/06/13 11:37] (aktuell)
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| Perennial herb, up to 60cm tall, native to Korea, China and Japan, extensively cultivated there; leaves 2-pinnately compound, leaflets ovate to laceolate, serrate; flowers in large compound umbels, white. \\ | Perennial herb, up to 60cm tall, native to Korea, China and Japan, extensively cultivated there; leaves 2-pinnately compound, leaflets ovate to laceolate, serrate; flowers in large compound umbels, white. \\ |
| The dried rhizome is used for woman' diseases, anaemia, weekness and pain. The drug is regarded as vasodilating, sedative, intestinal lood flow increasing, antifebrile, antispasmodic, antibacterial, inotrope, and antioxidant. \\ | The dried rhizome is used for woman' diseases, anaemia, weekness and pain. The drug is regarded as vasodilating, sedative, intestinal blood flow increasing, antifebrile, antispasmodic, antibacterial, inotrope, and antioxidant. \\ |
| [Medicinal Plants in the Republic of Korea World Health Organisation, Manila, 1998, 776-77] | [Medicinal Plants in the Republic of Korea World Health Organisation, Manila, 1998, 776-77] |
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| "Chunkung is one of the important folk medicines for counteracting a variety of diseases, and is particularly used as a traditional oriental medicine in the treatment of female genital inflammatory diseases. Sixty-eight volatile flavour constituents, which make up 95.7% of the total volatile content of the oil, were detected in chunkung essential oil, which contained 25 hydrocarbons (15.9%), eight aldehydes (0.7%), 13 alcohols (11.5%), three ketones (0.5%), nine esters (1.4%), three oxides (0.4%), one acid (trace), five phthalides (64.8%) and one miscellaneous component (0.1%). cis-Butylidene phthalide (33.2%) was the most abundant component followed by 3-butyl phthalide (21.1%), cis-3-isobutylidene phthalide (10.1%) and terpinen-4-ol (8.5%)." \\ | "Chunkung is one of the important folk medicines for counteracting a variety of diseases, and is particularly used as a traditional oriental medicine in the treatment of female genital inflammatory diseases. Sixty-eight volatile flavour constituents, which make up 95.7% of the total volatile content of the oil, were detected in chunkung essential oil, which contained 25 hydrocarbons (15.9%), eight aldehydes (0.7%), 13 alcohols (11.5%), three ketones (0.5%), nine esters (1.4%), three oxides (0.4%), one acid (trace), five phthalides (64.8%) and one miscellaneous component (0.1%). cis-Butylidene phthalide (33.2%) was the most abundant component followed by 3-butyl phthalide (21.1%), cis-3-isobutylidene phthalide (10.1%) and terpinen-4-ol (8.5%)." \\ |
| [Constituents of the essential oil of cnidium officinale Makino, a Korean medicinal plant., Choi, H.S., Kim, M.S.L., Sawamura, M., Flavour and fragrance journal, Vol.17(1), 2002, 49-53] | [Constituents of the essential oil of Cnidium officinale Makino, a Korean medicinal plant., Choi, H.S., Kim, M.S.L., Sawamura, M., Flavour and fragrance journal, Vol.17(1), 2002, 49-53] |
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| "The [dried] rhizomes of C. officinale (Cinidii Rhizoma)... are used in the treatment of pain, inflammation, menstrual disturbance, and anti-vitamin deficiency disease, and also act as a blood pressure depressant. In addition, there are several reports suggesting that they have pharmacological properties to tumor metastasis and angiogenesis and that they act as an inhibitor of high glucose-induced proliferation of glomerular mesangial cells... C.officinale and L. chuanxiong are closely related species with 98% of sequence identity... C. officinale had the greatest activity to quench NO radical. The IC50 values were 57.25 and 76.50 µg/ml for C. officinale and L. chuanxiong, respectively. [control: ascrobic acid 9.88µg/ml]" \\ | "The [dried] rhizomes of C. officinale (Cinidii Rhizoma)... are used in the treatment of pain, inflammation, menstrual disturbance, and anti-vitamin deficiency disease, and also act as a blood pressure depressant. In addition, there are several reports suggesting that they have pharmacological properties to tumor metastasis and angiogenesis and that they act as an inhibitor of high glucose-induced proliferation of glomerular mesangial cells... C.officinale and L. chuanxiong are closely related species with 98% of sequence identity... C. officinale had the greatest activity to quench NO radical. The IC50 values were 57.25 and 76.50 µg/ml for C. officinale and L. chuanxiong, respectively. [control: ascrobic acid 9.88µg/ml]" \\ |
| [Components of rhizome extract of Cnidium officinale Makino and their in vitro biological effects., Bae, K.E., Choi, Y.W., Kim, S.T., Kim, Y.K., Molecules, Vol.16(10), 2011, 8833-8847] \\ | [Components of rhizome extract of Cnidium officinale Makino and their in vitro biological effects., Bae, K.E., Choi, Y.W., Kim, S.T., Kim, Y.K., Molecules, Vol.16(10), 2011, 8833-8847] \\ |
| [[http://mdpi.com/1420-3049/16/10/8833/pdf]] | [[http://mdpi.com/1420-3049/16/10/8833/pdf]] |
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| | "GC/MS analyses were carried out with the direct- and solid phase microextraction (SPME) of SFE obtained from rhizomes. In addition, GC/MS analysis was performed for the rhizomes of C. officinale using SPME... SPME-GC/MS analysis of the rhizomes revealed the separation of 23 components. Among these, β-phellandrene (20.38%), dictyotene (12.98%), β-pinene (10.59%), β-selinene (9.45%), eugenol (7.71%) and β-farnesene (7.09%) were found to be major components. In the SFE analyzed by direct-GC/MS, linoleic acid (19.26%), 2-methoxy-4-vinylphenol (18.98%), hexadecanoic acid (12.15%), and β-selinene (9.44%) were identified as major components. Whereas, 3,4-dihydrocoumarin (16.94%), shyobunone (14.07%), dictyotene (10.65%), p-cresol (10.17%), zierone (6.36%) and umbellulone (5.71%) were major components in the SFE analyzed by SPME-GC/MS." \\ |
| | [Comparison of volatile composition of supercritical carbon dioxide extract from rhizomes of Korean medicinal plant ‘CHUN-KUNG’ (Cnidium officinale Makino) by direct - and SPME-GC/MS., Kim, S., Yeon, B.R., Sowndhararajan, K., Jung, J.W., Jhoo, J.W. International Journal of Pharmacy and Pharmaceutical Sciences, 6(9), 2014, ] \\ |
| | [[http://www.innovareacademics.in/journals/index.php/ijpps/article/viewFile/2249/pdf_193]] |
