| Beide Seiten der vorigen RevisionVorhergehende ÜberarbeitungNächste Überarbeitung | Vorhergehende Überarbeitung |
| valeriana_fauriei_briq [2014/08/29 11:45] – andreas | valeriana_fauriei_briq [2015/06/13 09:40] (aktuell) – Externe Bearbeitung 127.0.0.1 |
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| [ Medicinal Plants in the Republic of Korea World Health Organisation, Manila ISBN 92 9061 120 0 (1998)] | [ Medicinal Plants in the Republic of Korea World Health Organisation, Manila ISBN 92 9061 120 0 (1998)] |
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| | "Antidepressant activity-guided fractionation of the MeOH extract of Valeriana fauriei Briq. roots resulted in the isolation of two new germacrane-type sesquiterpenes (1–2) in addition to seven known ones (3–9). Their structures were elucidated as 1β,10α-dihydroxyl-8α-acetoxyl-10β,11,11-trimethyl-4-formyl-bicyclogermacren-E-4(5)-ene (1), 1β-hydroxyl-8α-acetoxyl-11,11-dimethyl-4-formyl-bicyclogermacren-E-4(5),10(14)-diene (2), bicyclo[8,1,0]5β-hydroxyl-7β-1acetoxyl-5α,11,11′-trimethyl -E-1(10)-ene-4α,15-olide (3), 8α-acetoxyl-3α,4α,10-trihydroxyl-guaia-1(2)-ene-12,6α-olide (4), 2-Ethylhexyl-4-hydroxybenzoate (5), 11αH-gemacra-1(10)E,4Z-diene-3-one-12,6α-olide (6), β-Sitoterol (7), isovaleric acid (8), isoborneol acetate (9), using a combination of UV, IR, mass spectroscopy, 1D and 2D NMR spectroscopy. The antidepressant activity of compounds 1–4 was investigated by the FST on mice. Among them, compounds 3 and 4 showed the significant antidepressant activity (*, P < 0.01)." \\ |
| | [In vivo antidepressant activity of sesquiterpenes from the roots of //Valeriana fauriei// Briq., Liu, X. G., Gao, P. Y., Wang, G. S., Song, S. J., Li, L. Z., Li, X., Zhang, Z. X., Fitoterapia, Vol.83(3), 2012, 599-603] |
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