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glycyrrhiza_uralensis_fisch._ex_dc [2015/07/14 14:02] andreasglycyrrhiza_uralensis_fisch._ex_dc [2016/10/28 07:15] (aktuell) andreas
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 [Anti-Helicobacter pylori flavonoids from licorice extract., Fukai, T., Marumo, A., Kaitou, K., Kanda, T., Terada, S., Nomura, T., Life sciences, 71(12), 2002, 1449-1463] [Anti-Helicobacter pylori flavonoids from licorice extract., Fukai, T., Marumo, A., Kaitou, K., Kanda, T., Terada, S., Nomura, T., Life sciences, 71(12), 2002, 1449-1463]
  
-"About the six main constituents of licorice of glycyrrhizin, liquiritin, liquiritin apioside, isoliquiritin,  soliquiritin apioside, and liquiritigenin, the constituent property of G.glabra resembles to that of G.inflata, but that of G.uralensis does not resemble to that of G.glabra or G.inflata and is characterized by a wider content variation of the six main constituents of licorice than that of G.glabra or G.inflata. The mean contents of liquiritin, isoliquiritin, and liquilitigenin in G.uralensis are significantly higher than those of G.glabra and G.inflata. Especially, the mean contet of liquiritin in G.uralensis is higher more than 1% compared to that of G.glabra or G.inflata. Additionally, glycycoumarin, glabridin, or licochalcone A are reconfirmed as the species-specific constituents for G.uralensis, G.glabra, or G.inflata respectively." \\+"About the six main constituents of licorice of glycyrrhizin, liquiritin, liquiritin apioside, isoliquiritin,  soliquiritin apioside, and liquiritigenin, the constituent property of G.glabra resembles to that of G.inflata, but that of G.uralensis does not resemble to that of G.glabra or G.inflata and is characterized by a wider content variation of the six main constituents of licorice than that of G.glabra or G.inflata. The mean contents of liquiritin, isoliquiritin, and liquilitigenin in G.uralensis are significantly higher than those of G.glabra and G.inflata. Especially, the mean content of liquiritin in G.uralensis is higher more than 1% compared to that of G.glabra or G.inflata. Additionally, glycycoumarin, glabridin, or licochalcone A are reconfirmed as the species-specific constituents for G.uralensis, G.glabra, or G.inflata respectively." \\
 [Constituent properties of licorices derived from Glycyrrhiza uralensis, G. glabra, or G. inflata identified by genetic information. Kondo, K., Shiba, M., Nakamura, R., Morota, T., & Shoyama, Y. , Biological and Pharmaceutical Bulletin, Vol.30(7), 2007, 1271-1277] [Constituent properties of licorices derived from Glycyrrhiza uralensis, G. glabra, or G. inflata identified by genetic information. Kondo, K., Shiba, M., Nakamura, R., Morota, T., & Shoyama, Y. , Biological and Pharmaceutical Bulletin, Vol.30(7), 2007, 1271-1277]
  
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 [Anti-inflammatory effects of glycyrol isolated from Glycyrrhiza uralensis in LPS-stimulated RAW264.7 macrophages, Eun Myoung Shin et al., International Immunopharmacology, Vol.8(11), 2008, 1524–1532] [Anti-inflammatory effects of glycyrol isolated from Glycyrrhiza uralensis in LPS-stimulated RAW264.7 macrophages, Eun Myoung Shin et al., International Immunopharmacology, Vol.8(11), 2008, 1524–1532]
  
-{{http://kegg.jp/Fig/compound_small/C16968.gif}} [[http://equilibrator.weizmann.ac.il/compound?compoundId=C16968|glycyrol]]+{{glycyrol.jpg}} [[http://www.chemspider.com/Chemical-Structure.4478245.html|glycyrol]]
  
 Isoliquiritigenin (IC50 = 9.0 μM) and glycyrol (IC50 = 3.1 μM) from G.uralensis have strong neuraminidase inhibitor activity. \\ Isoliquiritigenin (IC50 = 9.0 μM) and glycyrol (IC50 = 3.1 μM) from G.uralensis have strong neuraminidase inhibitor activity. \\
-[Inhibition of neuraminidase activity by polyphenol compounds isolated from the roots of //Glycyrrhiza uralensis//. Ryu, Y. B., Kim, J. H., Park, S. J., Chang, J. S., Rho, M. C., Bae, K. H., ... & Lee, W. S., Bioorganic & medicinal chemistry letters, Vol.20(3), 2010, 971-974] +[Inhibition of neuraminidase activity by polyphenol compounds isolated from the roots of //Glycyrrhiza uralensis//. Ryu, Y.B., Kim, J.H., Park, S.J., Chang, J.S., Rho, M.C., Bae, K.H., Lee, W.S., Bioorganic & medicinal chemistry letters, Vol.20(3), 2010, 971-974] \\ 
 +[Influenza neuraminidase: A druggable target for natural products., Grienke, U., Schmidtke, M., von Grafenstein, S., Kirchmair, J., Liedl, K.R., Rollinger, J.M., Natural product reports, 29(1), 2012, 11-36] [[http://pubs.rsc.org/en/content/articlehtml/2012/np/c1np00053e]] 
 + 
 +The total amounts of 14 main compounds (liquiritin apioside, liquiritin, isoliquiritin apioside, licorice glycoside D2, 4'-dihydroxyflavone, liquiritigenin, echinatin, isoliquiritigenin, formonoetin, glycyrrhizic  
 +acid, licoflavone A, licoflavone C, 4'-hydroxy-2",2"-dimethylpyrano [5", 6": 6,7]flavone, and licochalcone) from licorice root samples of Chinese origin varied from 19.1 to 66.0 mg/g , with glycyrrhizic acid 7.0-25.9 mg/g. \\ 
 +[Simultaneous determination and assignment of 13 major flavonoids and glycyrrhizic acid in licorices by HPLC-DAD and Orbirap mass spectrometry analyses., Shan-Shan, W., Min, Y., Xin, C., Qiu-Rong, W., Ya-Jun, C., Chinese journal of natural medicines, 13(3), 2015, 232-240] \\ 
 +[[http://www.wasstop.com/uploadfile/2015/0417/20150417015844253.pdf]] 
 + 
 + 
 +picture: Flora of China [[http://www.efloras.org/object_page.aspx?object_id=116740&flora_id=2]]
  
glycyrrhiza_uralensis_fisch._ex_dc.1436882533.txt.gz · Zuletzt geändert: 2015/07/14 14:02 von andreas

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