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cyperus_scariosus_r._br [2025/12/10 11:37] andreascyperus_scariosus_r._br [2025/12/10 11:37] (aktuell) andreas
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 "... the demand for cypriol has increased because of its unique woody, ambery, and earthy character that is appreciated by perfumers as an alternative to the more expensive agarwood oil which is difficult to reproduce synthetically... Rotundone was found to have the highest odor-activity value of the measured compounds and, together with the other ketones, contributes to the woody-amber character of cypriol oil." \\ "... the demand for cypriol has increased because of its unique woody, ambery, and earthy character that is appreciated by perfumers as an alternative to the more expensive agarwood oil which is difficult to reproduce synthetically... Rotundone was found to have the highest odor-activity value of the measured compounds and, together with the other ketones, contributes to the woody-amber character of cypriol oil." \\
 Of the 21 nitrogen components reported from the essential oil of Cyperus scariosus, epi-guaipyridine (32 mg/kg), guaia-9,11-dienpyridine (9 mg/kg), and cananodine (10 mg/kg) were the most abundant. A new ketone with a significant woody ambery odor, cyperen-8-one,  could also be isolated. Potent compounds with an odor activity value (OAV) >1 were cyperen-8-one (2.3), nootkatone (2.9), cyperotundone (6.9), and rotundone (500). \\ Of the 21 nitrogen components reported from the essential oil of Cyperus scariosus, epi-guaipyridine (32 mg/kg), guaia-9,11-dienpyridine (9 mg/kg), and cananodine (10 mg/kg) were the most abundant. A new ketone with a significant woody ambery odor, cyperen-8-one,  could also be isolated. Potent compounds with an odor activity value (OAV) >1 were cyperen-8-one (2.3), nootkatone (2.9), cyperotundone (6.9), and rotundone (500). \\
-[Constituents of Cypriol Oil (Cyperus scariosus R. Br.): N-Containing Molecules and Key Aroma Components., Clery, R.A., Cason, J.R., Zelenay, V., Journal of agricultural and food chemistry., 4566-4573, 2016] +[Constituents of Cypriol Oil (Cyperus scariosus R. Br.): N-Containing Molecules and Key Aroma Components., Clery, R.A., Cason, J.R., Zelenay, V., Journal of agricultural and food chemistry., 4566-4573, 2016] [[http://pubs.acs.org/doi/abs/10.1021/acs.jafc.6b00680|PDF]]
  
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 In the acetic acid-induced writhing model mice, administration of a //methanol extract from C.scariosus leaves// showed  significant dose-dependent inhibition with maximum inhibition of writhing (46.62%) obtained at 200mg extract/kg body weight, whereas the standard antinociceptive drug, aspirin caused 56.74% writhing inhibition at the same dose. \\ In the acetic acid-induced writhing model mice, administration of a //methanol extract from C.scariosus leaves// showed  significant dose-dependent inhibition with maximum inhibition of writhing (46.62%) obtained at 200mg extract/kg body weight, whereas the standard antinociceptive drug, aspirin caused 56.74% writhing inhibition at the same dose. \\
 Higher doses (400mg/kg body weight) of the methanol extract exhibited significant anti-hyperglycemic activity in glucose-induced hyperglycemic mice. The maximum inhibition effect at this dosage was close to that of the standard drug glibenclamide (10mg/kg body weight). \\  Higher doses (400mg/kg body weight) of the methanol extract exhibited significant anti-hyperglycemic activity in glucose-induced hyperglycemic mice. The maximum inhibition effect at this dosage was close to that of the standard drug glibenclamide (10mg/kg body weight). \\ 
-[Antinociceptive and anti-hyperglycemic activity of methanol leaf extract of Cyperus scariosus., Alam, M.A., Jahan, R., Rahman, S., Das, A.K., Rahmatullah, M., Pak J Pharm Sci, 24(1), 2011, 53-60] [[http://www.pjps.pk/wp-content/_uploads/pdfs/CD-PJPS-24-1-11/Paper-10.pdf|PDF]]+[Antinociceptive and anti-hyperglycemic activity of methanol leaf extract of Cyperus scariosus., Alam, M.A., Jahan, R., Rahman, S., Das, A.K., Rahmatullah, M., Pak J Pharm Sci, 24(1), 2011, 53-60]  
  
 {{:cyperus_scariosus.jpg?700}} \\ {{:cyperus_scariosus.jpg?700}} \\
cyperus_scariosus_r._br.txt · Zuletzt geändert: 2025/12/10 11:37 von andreas

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