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Galega officinalis L. - syn.Galega bicolor Boiss. & Hausskn. ex Regel; Galega patula Steven - Fabaceae - galega, goat's rue, Echte Geißraute
Erect perennial, up to 150 cm tall, Europe, West Asia (Turkey, Pakistan), naturalized and cultivated; leaves pinnate, leaflets 9-21, up to 5cm long, elliptic to lanceolate; inflorescence a 25-50-flowered raceme; flowers white to purple; fruit 20-50cm long, c.2-3mm broad, 2-10-seeded.
http://www.efloras.org/florataxon.aspx?flora_id=5&taxon_id=220005407
„Galegine was isolated as an active anti-hyperglycemic agent from the plant Galega officinalis L. This plant was used ethnomedically for the treatment of diabetes. Galegine provided the template for the synthesis of metformin and opened up interest in the synthesis of other biguanidine-type antidiabetic drugs.“
[The value of plants used in traditional medicine for drug discovery., Fabricant, D.S., Farnsworth, N.R., Environmental health perspectives, 109(Suppl 1), 2001, 69] http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1240543/pdf/ehp109s-000069.pdf
„A fraction isolated from crude aqueous extract of Galega officinalis L. and purified by column chromatography inhibit platelet aggregation in platelet-rich plasma. The active fraction of the extract, molecular weight of 100–140 kDa, appeared to be polysaccharide-protein complex. Aggregation of platelets initiated by 25 μM ADP was inhibited 50 percent by 11.2 μg/ml of the fraction. Aggregation of platelets initiated by 100 μg/ml collagen and 0.8 U/ml thrombin was completely inhibited by 16 μg/ml and 18.3 μg/ml, respectively.“
[Antiplatelet aggregation activity of a fraction isolated from Galega officinalis L., Atanasov, A.T., Tchorbanov, B., Journal of herbs, spices & medicinal plants, 10(2), 2003, 63-71]
The dried aerial parts (Galega herba) are used traditionally as diuretic and especially as antidiabetic. „Is is still widely used in folk medicine, also to treat skin ulcers… The main active compound is galegine (up to 0.5%), a guanidine derivative that occurs together with 4-hydroxygalegine and quinoline alkaloids (up to 0.35%) such as geanine (vasicine) and vasicinone… The drug inhibits platelet aggregation, and exhibits hypoglycaemic and lactagogue activities.“
[Medicinal Plants of the World. Ben-Erik Van Wyk and Michael Wink, Pretoria 2004, 150]
Thomé, O.W., Flora von Deutschland Österreich und der Schweiz, Tafeln, vol. 3: t. 437 (1885)
http://plantgenera.org/species.php?id_species=449226