Benutzer-Werkzeuge

Webseiten-Werkzeuge


galega_officinalis_l

Dies ist eine alte Version des Dokuments!


Galega officinalis L. - syn.Galega bicolor Boiss. & Hausskn. ex Regel; Galega patula Steven - Fabaceae - galega, goat's rue, Echte Geißraute

Erect perennial, up to 150 cm tall, Europe, West Asia (Turkey, Pakistan), naturalized and cultivated; leavflets 9-21, up to 5cm long, elliptic to lanceolate; inflorescence a 25-50-flowered raceme; flowers white to purple; fruit 20-50cm long, c.2-3mm broad, 2-10-seeded.
http://www.efloras.org/florataxon.aspx?flora_id=5&taxon_id=220005407

„Galegine was isolated as an active anti-hyperglycemic agent from the plant Galega officinalis L. This plant was used ethnomedically for the treatment of diabetes. Galegine provided the template for the synthesis of metformin and opened up interest in the synthesis of other biguanidine-type antidiabetic drugs.“
[The value of plants used in traditional medicine for drug discovery., Fabricant, D.S., Farnsworth, N.R., Environmental health perspectives, 109(Suppl 1), 2001, 69] http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1240543/pdf/ehp109s-000069.pdf

The dried aerial parts (Galega herba) are used traditionally as diuretic and especially as antidiabetic. „Is is still widely used in folk medicine, also to treat skin ulcers… The main active compound is galegine (up to 0.5%), a guanidine derivative that occurs together with 4-hydroxygalegine and quinoline alkaloids (up to 0.35%) such as geanine (vasicine) and vasicinone… The drug inhibits platelet aggregation, and exhibits hypoglycaemic and lactagogue activities.“
[Medicinal Plants of the World. Ben-Erik Van Wyk and Michael Wink, Pretoria 2004, 150]

galega_officinalis_l.1437307398.txt.gz · Zuletzt geändert: 2015/07/19 12:03 von andreas

Donate Powered by PHP Valid HTML5 Valid CSS Driven by DokuWiki