Unterschiede

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--- paris_quadrifolia_l [2016/02/21 16:37] – andreas
+++ paris_quadrifolia_l [2016/02/21 16:43] (aktuell) – andreas
@@ Zeile 5: / Zeile 5: @@
 [Biological Flora of the British Isles: Paris quadrifolia L., Jacquemyn, H., Brys, R., Hutchings, M.J., Journal of ecology, 96(4), 2008, 833-844] [[http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2745.2008.01397.x/full]]
-The crushed fresh herb was used externally in former times to treat wounds and ulcers, ailments of the eyes (doctrine of signatures: eye-resembling berry) and internally (rhizome) as emetic. Today the herb of P.quadrifolia is only used in homoepathic preparations to treat headache, inflammation of the upper respiratory system and problems with sense of smell and touch. \\
+The crushed fresh herb was used externally in former times to treat wounds and ulcers, ailments of the eyes (doctrine of signatures: eye-resembling berry) and internally (rhizome) as emetic. Today the herb of P.quadrifolia is only used in homoepathic preparations to treat headache, inflammation of the upper respiratory system and problems with senses of smell and touch. \\
 [Hagers Handbuch der Pharmazeutischen Praxis, Springer 2010]
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 Pennogenyl saponins pennogenin 3-O-α-L-rhamnopyranosyl-(1→4)-[α-L-rhamnopyranosyl-(1→2)]-β-D-glucopyranoside and pennogenin 3-O-α-L-rhamnopyranosyl-(1→4)-α-L-rhamnopyranosyl-(1→4)-[α-L-rhamnopyranosyl-(1→2)]-β-D-glucopyranoside exhibited strong cytotoxic activity against HL-60, HeLa and MCF-7 tumour cells. \\
 [Isolation and identification of cytotoxic compounds from the rhizomes of Paris quadrifolia L., Gajdus, J., Kaczyński, Z., Kawiak, A., Łojkowska, E., Stefanowicz-Hajduk, J., Ochocka, J.R., Stepnowski, P., Pharmacognosy magazine, 10(Suppl 2), 2014, S324]
+Regarding the the molecular mechanisms of cytotoxic effects of pennogenyl saponins, both the extrinsic death receptor and intrinsic mitochondrial pathways are involved in the programmed cell death. \\
+[Pennogenyl Saponins from Paris quadrifolia L. Induce Extrinsic and Intrinsic Pathway of Apoptosis in Human Cervical Cancer HeLa Cells., Stefanowicz-Hajduk, J., Bartoszewski, R., Bartoszewska, S., Kochan, K., Adamska, A., Kosiński, I., Ochocka, J.R., PloS one, 10(8), 2015, e0135993] [[http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0135993]]
 {{:paris_quadrifolia.jpg?500|}} \\
 Redouté, P.J., Les Liliacées, vol.4 t.226 (1805-1816) \\
 [[http://plantgenera.org/species.php?id_species=749983]]