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iberis_amara_l [2015/10/22 08:31] andreasiberis_amara_l [2017/07/01 09:25] (aktuell) andreas
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 Iberis amara L. - syn. Iberis coronaria D. Don - Brassicaceae - bitter candytuft, rocket candytuft, **Bittere Schleifenblume**, Bitterer Bauernsenf Iberis amara L. - syn. Iberis coronaria D. Don - Brassicaceae - bitter candytuft, rocket candytuft, **Bittere Schleifenblume**, Bitterer Bauernsenf
  
-Annual herb, up to 40cm high, native to Western EuropeMediterranean, naturalized in the Americas, NewZealand; leaves spatulate or oblanceolate to oblong, dentate; flowers in racemes, small, irregular, white or pink to purple. [[http://www.efloras.org/florataxon.aspx?flora_id=1&taxon_id=200009565]]+Annual herb, up to 40cm high, native to Western Europe and the Mediterranean, naturalized in America and New Zealand; leaves spatulate or oblanceolate to oblong, dentate; flowers in racemes, small, irregular, white or pink to purple. [[http://www.efloras.org/florataxon.aspx?flora_id=1&taxon_id=200009565]
 + 
 +[[http://pubchem.ncbi.nlm.nih.gov/compound/9548621|Glucoiberin]] (3-methylsulfinylpropyl glucosinolate) has been found in the roots, herb and seeds of I.amara. The bitter agent ibamarin was isolated from the seeds. \\ 
 +[Das Senfölglukosid „Glukoiberin” ︁ und der Bitterstoff „Ibamarin” ︁ von Iberis amara L.(Schleifenblume). IX. Mitteilung über Senfölglukoside., Schultz, O.E., Gmelin, R., Archiv der Pharmazie, 287(7), 1954, 404-411] 
 + 
 +The cytotoxic and bitter tasting triterpenes [[https://en.wikipedia.org/wiki/Cucurbitacin_E|cucurbitacin E]] and cucurbitacin I have been isolated from green parts of Iberis amara. \\ 
 +[Cucurbitacin E and I in Iberis amara: Feeding inhibitors for Phyllotreta nemorum., Nielsen, J.K., Larsen, L. M., Sørensen H., Phytochemistry, 16(10), 1977, 1519-1522] 
 + 
 +3-Methylthiopropylamine and (R)-3-methylsulphinylpropylamine have been isolated from Iberis amara. \\ 
 +[3-Methylthiopropylamine and (R)-3-methylsulphinylpropylamine in Iberis amara., Dalgaard, L., Nawaz, R., Sørensen, H., Phytochemistry, 16(7), 1977, 931-932]
  
 "In pharmacological studies both in vitro (e.g., in guinea pig ileum) and in vivo (e.g., in Wistar rats) the fresh plant extract of Iberis amara (IF) exhibited a tonicising effect on the smooth muscles of the stomach and small intestine. In the rat IF produced a dose-dependent antiulcerogenic effect (indomethacin-induced ulcer) comparable to that of cimetidine (reference substance). The stomach acid release and the leucotriene-concentration, increased by indomethacin, were reduced by IF, whereas the prostaglandin E2 content, reduced by indomethacin, was increased. In patients with irritable bowel syndrome as a subtypological symptom associated with diarrhea and in patients with alternating diarrhea and obstipation, clear differences were found between drug and placebo in a multicenter, prospective, double-blind, randomized parallel group comparison." \\ "In pharmacological studies both in vitro (e.g., in guinea pig ileum) and in vivo (e.g., in Wistar rats) the fresh plant extract of Iberis amara (IF) exhibited a tonicising effect on the smooth muscles of the stomach and small intestine. In the rat IF produced a dose-dependent antiulcerogenic effect (indomethacin-induced ulcer) comparable to that of cimetidine (reference substance). The stomach acid release and the leucotriene-concentration, increased by indomethacin, were reduced by IF, whereas the prostaglandin E2 content, reduced by indomethacin, was increased. In patients with irritable bowel syndrome as a subtypological symptom associated with diarrhea and in patients with alternating diarrhea and obstipation, clear differences were found between drug and placebo in a multicenter, prospective, double-blind, randomized parallel group comparison." \\
iberis_amara_l.1445502676.txt.gz · Zuletzt geändert: 2015/10/22 08:31 von andreas

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