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--- frangula_purshiana_dc._a._gray [2014/11/28 11:29] – andreas
+++ frangula_purshiana_dc._a._gray [2015/06/13 09:38] (aktuell) – Externe Bearbeitung 127.0.0.1
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 "A tree, 4-10m high, with reddish-brown bark and hairy twigs. Leaves petiolate, elliptical, acuminate, serrulate, or sometimes entire, with 10-15 pairs of veins, dull green upper surface and pubescent underside. Inflorescence an axillary umbellate cyme of small greenish flowers. Fruit a turbinate, purplish-black drupe, about 8mm long, composed of 3 indehiscent cocci. \\
 The fresh bark contains free anthrones and must be dried for at least 1 year or artificially aged by heat or aeration before therapeutic use. \\
-Contains not less than 8.0% hydroxyanthracene glycosides of which not less than 60% consists of cascarosides, both calculated as cascaroside A. Quantitative analysis is performed by spectrophotometry at 515nm (3, 5). A highperformance liquid chromatography method for the quantitative analysis of cascarosides has been reported.
+Contains not less than 8.0% hydroxyanthracene glycosides of which not less than 60% consists of cascarosides, both calculated as cascaroside A. Quantitative analysis is performed by spectrophotometry at 515nm. A high performance liquid chromatography method for the quantitative analysis of cascarosides has been reported.
-The active constituents are hydroxyanthracene glycosides (6-9%). Of these, 70-90% are C-10 glycosides, with the 8-O-glycosides, aloins A and B, and 11-desoxyaloins A and B (chrysaloins A and B) accounting for 10-30%. The diastereoisomeric pairs, cascarosides A and B and cascarosides C and D and cascarosides E and F constitute 60-70% of the total O-glycosides. Other major hydroxyanthracene glycosides (10-20%) include the hydroxyanthraquinones, chrysophanol-8-O-glucoside and aloe-emodin-8-O-glucoside." \\
+The active constituents are hydroxyanthracene glycosides (6-9%). Of these, 70-90% are C-10 glycosides, with the 8 -O-glycosides, aloins A and B, and 11-desoxyaloins A and B (chrysaloins A and B) accounting for 10-30%. The diastereoisomeric pairs, cascarosides A and B and cascarosides C and D and cascarosides E and F constitute 60-70% of the total O-glycosides. Other major hydroxyanthracene glycosides (10-20%) include the hydroxyanthraquinones, chrysophanol-8 -O-glucoside and aloe-emodin-8 -O-glucoside." \\
 [Cortex Rhamni Purshianae, WHO Monographs on Selected Medicinal Plants - Volume 2, 2004] [[http://apps.who.int/medicinedocs/en/d/Js4927e/25.html#Js4927e.25]]