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withania_somnifera_l._dun [2015/04/26 12:38]
andreas 		withania_somnifera_l._dun [2015/10/14 12:26] (aktuell)
andreas
Zeile 6: Zeile 6:
 "The (Ashwagandha) and its root are due to their versatile effects one of the most frequently used drugs in Ayurvedic medicine. It may be compared in importance with that of ginseng for the Chinese medicine. They are used to thread impotence, inflammation and insomnia."  \\ "The (Ashwagandha) and its root are due to their versatile effects one of the most frequently used drugs in Ayurvedic medicine. It may be compared in importance with that of ginseng for the Chinese medicine. They are used to thread impotence, inflammation and insomnia."  \\
 [[http://de.wikipedia.org/wiki/Withania_somnifera]] [[http://de.wikipedia.org/wiki/Withania_somnifera]]
 +
 +"A methanolic extract of W. somnifera root inhibited the specific binding of [3H]GABA and [35S]TBPS, and enhanced the binding of [3H]flunitrazepam to their putative receptor sites... In functional studies using 36Cl-influx assay in mammalian spinal cord neurons, W. somnifera root extract increased 36Cl-influx in the absence of GABA. This effect on 36Cl-influx was blocked by bicuculline and picrotoxin; and enhanced by diazepam. These results suggest that the W. somnifera extract contains an ingredient which has a GABA-mimetic activity." \\
 +[Pharmacological effects of Withania somnifera root extract on GABAA receptor complex., Mehta, A.K., Binkley, P., Gandhi, S.S., Ticku, M.K., The Indian journal of medical research, Vol.94, 1991, 312-315.] 
  
 "The roots of Withania somnifera (WS) are used extensively in Ayurveda, the classical Indian system of medicine, and WS is categorized as a rasayana, which are used to promote physical and mental health, to provide defence against disease and adverse environmental factors and to arrest the aging process. WS has been used to stabilize mood in patients with behavioural disturbances. The present study investigated the anxiolytic and antidepressant actions of the bioactive glycowithanolides (WSG), isolated from WS roots, in rats... WSG induced an anxiolytic effect, comparable to that produced by lorazepam, in the elevated plus-maze, social interaction and feeding latency in an unfamiliar environment, tests. Further, both WSG and lorazepam, reduced rat brain levels of tribulin, an endocoid marker of clinical anxiety, when the levels were increased following administration of the anxiogenic agent, pentylenetetrazole. WSG also exhibited an antidepressant effect, comparable with that induced by imipramine, in the forced swim-induced ‘behavioural despair’ and ‘learned helplessness’ tests. The investigations support the use of WS as a mood stabilizer in clinical conditions of anxiety and depression in Ayurveda." \\ "The roots of Withania somnifera (WS) are used extensively in Ayurveda, the classical Indian system of medicine, and WS is categorized as a rasayana, which are used to promote physical and mental health, to provide defence against disease and adverse environmental factors and to arrest the aging process. WS has been used to stabilize mood in patients with behavioural disturbances. The present study investigated the anxiolytic and antidepressant actions of the bioactive glycowithanolides (WSG), isolated from WS roots, in rats... WSG induced an anxiolytic effect, comparable to that produced by lorazepam, in the elevated plus-maze, social interaction and feeding latency in an unfamiliar environment, tests. Further, both WSG and lorazepam, reduced rat brain levels of tribulin, an endocoid marker of clinical anxiety, when the levels were increased following administration of the anxiogenic agent, pentylenetetrazole. WSG also exhibited an antidepressant effect, comparable with that induced by imipramine, in the forced swim-induced ‘behavioural despair’ and ‘learned helplessness’ tests. The investigations support the use of WS as a mood stabilizer in clinical conditions of anxiety and depression in Ayurveda." \\
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 {{:withania_somnifera.jpg?500}} \\ {{:withania_somnifera.jpg?500}} \\
 Kirtikar, K.R., Basu, B.D., Indian medicinal plants, Plates, vol.4, t.681 (1918) \\ Kirtikar, K.R., Basu, B.D., Indian medicinal plants, Plates, vol.4, t.681 (1918) \\
-[[http://plantgenera.org/species.php?id_species=1075114]]+[[http://plantgenera.org/species.php?id_species=1075114]] \\
  
 +{{http://upload.wikimedia.org/wikipedia/commons/4/48/Aswagandhaherb11.jpg}} \\
 +Aswagandha plant and roots, [[https://commons.wikimedia.org/wiki/Withania_somnifera?uselang=de#/media/File:Aswagandhaherb11.jpg|source: wikimedia]] Author: Piouswatson
    
withania_somnifera_l._dun.1430044715.txt.gz · Zuletzt geändert: 2015/04/26 12:38 von andreas

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