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valeriana_officinalis_l [2019/02/21 14:14]
andreas
valeriana_officinalis_l [2022/10/24 14:46] (aktuell)
andreas
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 [[http://ods.od.nih.gov/factsheets/Valerian-HealthProfessional/]] [[http://ods.od.nih.gov/factsheets/Valerian-HealthProfessional/]]
  
 +**flowers** \\
 +The flower scent of living V.officinalis is rather a sweet one and does not contain the unpleasant smelling valeric acid or isovaleric acid which are major components of the hydrodistilled flower oil. Headspace samples from unpicked valerian flowers contained lavandulyl isovalarate (15.0%), lavandulyl 2-methylbutyrate (0.6%), and lavandulol (1.6%), (E,E)-α-farnesene (7.6%), 3,4-dimethoxytoluene (4.7%), (Z)-3-hexenyl acetate (4.5%), p-methylanisol (3.6%) and methyl eugenol (2.1%). \\
 +[Flower scent of some traditional medicinal plants., Brunke, E.J., Hammerschmidt, F.J., Schmaus, G., In ACS symposium series (USA), 1993, 282-295] 
 +
 +**roots** \\
 Among the many sesquiterpenoid compounds present in V.officinalis root oil, (-)-maaliol sticks out: The higher the content, the finer the character of the scent of the oil. The actual scent carrier proved to be the ester of isovaleric acid with (-)-myrtenol. In addition, the acetates of (-)-myrtenol and (-)-borneol play an olfactory role. \\ Among the many sesquiterpenoid compounds present in V.officinalis root oil, (-)-maaliol sticks out: The higher the content, the finer the character of the scent of the oil. The actual scent carrier proved to be the ester of isovaleric acid with (-)-myrtenol. In addition, the acetates of (-)-myrtenol and (-)-borneol play an olfactory role. \\
 [Ohloff, Günther. "75 Jahre Riechstoff‐und Aroma‐Chemie im Spiegel der Helvetica Chimica Acta. Teil I." Helvetica Chimica Acta 75.5 (1992): 1341-1415] [Ohloff, Günther. "75 Jahre Riechstoff‐und Aroma‐Chemie im Spiegel der Helvetica Chimica Acta. Teil I." Helvetica Chimica Acta 75.5 (1992): 1341-1415]
- 
-The flower scent of living V.officinalis does not contain the unpleasant smelling valeric acid or isovaleric acid which are major components of the hydrodistilled flower oil. Headspace samples from unpicked valerian flowers contained lavandulyl isovalarate (15.0%), lavandulyl 2-methylbutyrate (0.6%), and lavandulol (1.6%), (E,E)-α-farnesene (7.6%), 3,4-dimethoxytoluene (4.7%), (Z)-3-hexenyl acteate (4.5%), p-methylanisol (3.6%) and methyl eugenol (2.1%). \\ 
-[Flower scent of some traditional medicinal plants., Brunke, E.J., Hammerschmidt, F.J., Schmaus, G., In ACS symposium series (USA), 1993, 282-295]  
  
 Main alkaloid of the root (0.03%) is N-(p-hydroxyphenyl)-ethyl actinidine, and the cat-attratractant [[http://www.kegg.jp/entry/C09910|actinidine]] is shown to be also present in the roots. \\ Main alkaloid of the root (0.03%) is N-(p-hydroxyphenyl)-ethyl actinidine, and the cat-attratractant [[http://www.kegg.jp/entry/C09910|actinidine]] is shown to be also present in the roots. \\
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-"A comprehensive search of studies investigating valerian was conducted through computerized databases and hand +"The data suggest that activation of adenosine A1 and GABA A receptors is mediated by different components within the valerian extract. The two mechanisms may contribute independently to the sleep-inducing effect of valerian." \\ 
-searches of reference lists. Standardized forms were used to summarize findings and standardized criteria were used to assess study quality. Out of 592 articles initially identified, a total of 36 articles describing 37 separate studies met criteria for review: 29 controlled trials evaluated for both efficacy and safety, and eight open-label trials evaluated for safety only. Most studies found no significant differences between valerian and placebo either in healthy individuals or in persons with general sleep disturbance or insomnia. None of the most recent studies, which were also the most methodologically rigorous, found significant effects of valerian on sleep. Overall, the evidence, while supporting that valerian is a safe herb associated with+[Sichardt, K., et al. "Modulation of postsynaptic potentials in rat cortical neurons by valerian extracts macerated with different alcohols: involvement of adenosine A1‐and GABA A‐receptors." Phytotherapy Research 21.10 (2007): 932-937] 
 + 
 +"A comprehensive search of studies investigating valerian was conducted through computerized databases and hand searches of reference lists. Standardized forms were used to summarize findings and standardized criteria were used to assess study quality. Out of 592 articles initially identified, a total of 36 articles describing 37 separate studies met criteria for review: 29 controlled trials evaluated for both efficacy and safety, and eight open-label trials evaluated for safety only. Most studies found no significant differences between valerian and placebo either in healthy individuals or in persons with general sleep disturbance or insomnia. None of the most recent studies, which were also the most methodologically rigorous, found significant effects of valerian on sleep. Overall, the evidence, while supporting that valerian is a safe herb associated with
 only rare adverse events, does not support the clinical efficacy of valerian as a sleep aid for insomnia" \\ only rare adverse events, does not support the clinical efficacy of valerian as a sleep aid for insomnia" \\
 [A systematic review of valerian as a sleep aid: safe but not effective. Taibi, D. M., Landis, C. A., Petry, H., Vitiello, M. V. , Sleep medicine reviews, Vol.11(3), 2007, 209-230] \\ [A systematic review of valerian as a sleep aid: safe but not effective. Taibi, D. M., Landis, C. A., Petry, H., Vitiello, M. V. , Sleep medicine reviews, Vol.11(3), 2007, 209-230] \\
valeriana_officinalis_l.1550754852.txt.gz · Zuletzt geändert: 2019/02/21 14:14 von andreas