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terminalia_sericea_roxb._wight_arn

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Combretaceae - silver cluster-leaf, silver terminalia

Deciduous tree, endemic to the southern Africa; bark reddish brown, peels away in strips; leaves crowded at the ends of branches, narrowly obovate-elliptic, blue-green above, paler below, densely covered in silvery hairs; flowers in axillary spikes, pale yellow to creamy white; fruit an oval nut, surrounded by a flat wing.
http://www.plantzafrica.com/planttuv/terminaliasericea.htm

„In traditional medicine, both leaves and roots have been used as a remedy for stomach ailments and a concoction of the roots for treating bilharzia, diarrhoea and pneumonia. The bark is used against diabetes and to dress wounds.“ https://en.wikipedia.org/wiki/Terminalia_sericea

„Bioassay-guided fractionation of an acetone extract of T. sericea stem bark led to the isolation of four known compounds namely β-sitosterol (1), β-sitosterol-3-acetate (2), lupeol (3), and stigma-4-ene-3-one (4), in addition to two inseparable sets of mixtures of isomers [epicatechin-catechin; (M1) and gallocatechin-epigallocatechin; (M2). 1 and 3 showed best inhibitory activity on α-glucosidase (IC50:54.5 μM and 66.48). The bio-evaluation of purified compound’s inhibitory activity on α-amylase, showed that lupeol and β-sitosterol exhibited IC50 values of 140.72 and 216.02 μM respectively against α-amylase. 2, M1, 3 and M2 were found to be non-toxic to Vero cells. This study is the first to report a-glucosidase, a-amylase of M1, M2, 2 and 4 isolated from T. sericea which validated the traditional use of the bark of T. sericea for diabetes in South Africa.“
[Nkobole, N., Houghton, P. J., Hussein, A. A., & Lall, N. (2011). Antidiabetic activity of Terminalia sericea Burch. Ex DC constituents.]

terminalia_sericea_roxb._wight_arn.1407076051.txt.gz · Zuletzt geändert: 2014/08/03 16:27 von andreas