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swertia_japonica_schult._makino [2015/03/11 13:53]
andreas 		swertia_japonica_schult._makino [2015/06/13 11:40] (aktuell)
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 Swertia japonica (Schult.) Makino - syn.Gentiana japonica Schult. - Gentianaceae \\ Swertia japonica (Schult.) Makino - syn.Gentiana japonica Schult. - Gentianaceae \\
-senburi (jap.), Swertia+senburi (jap.), **Swertia**
  
 Small annual herb, up to 20cm hogh, native to Japan and Korea; stem square, with branches; leaves opposite, linear or narrow lanceolate, 1-4cm long, 1-5mm width, entire, sessile; flowers with 5 stamens on the tube of the white corolla, which is splitted deeply into 5 narrow lobes.  Small annual herb, up to 20cm hogh, native to Japan and Korea; stem square, with branches; leaves opposite, linear or narrow lanceolate, 1-4cm long, 1-5mm width, entire, sessile; flowers with 5 stamens on the tube of the white corolla, which is splitted deeply into 5 narrow lobes. 
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 "Swertia herb (florescent whole plantof Swertia japonica, Gentianaceae) has long been utilized as a folk medicine in Japan. It is often blended in general gastroenteric drugs as a bitter stomachic. Swertiamarin, a bitter secoiridoid glycoside, is the representative constituent of this crude drug and Swertia herb is normally evaluated by the swertiamarin content." \\ "Swertia herb (florescent whole plantof Swertia japonica, Gentianaceae) has long been utilized as a folk medicine in Japan. It is often blended in general gastroenteric drugs as a bitter stomachic. Swertiamarin, a bitter secoiridoid glycoside, is the representative constituent of this crude drug and Swertia herb is normally evaluated by the swertiamarin content." \\
 [Analysis of swertiamarin in Swertia herb and preparations containing this crude drug by capillary electrophoresis., Takei, H., Nakauchi, K., Yoshizaki, F., Analytical sciences: the international journal of the Japan Society for Analytical Chemistry, Vol.17(7), 2001, 885-888] [Analysis of swertiamarin in Swertia herb and preparations containing this crude drug by capillary electrophoresis., Takei, H., Nakauchi, K., Yoshizaki, F., Analytical sciences: the international journal of the Japan Society for Analytical Chemistry, Vol.17(7), 2001, 885-888]
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 +{{:swertiamarin.jpg|}} [[http://www.sigmaaldrich.com/catalog/product/sigma/smb00080?lang=de&region=DE|swertiamarin]]
  
 S.japonica herb has been used as a stomachic or stimulant of appetite. Compounds found in the whole plant were the secoiridoid glycosides swertiajaposide A and swertiajaposide B, the unsaturated alcohol glycoside 3-butenyl 6'-O-α-L-arabinopyranosyl-β-D-glucopyranoside, the lignan glycoside 7R,7'R,8S,8'S-(+)-neo-olivil-4-O-β-D-glucopyranoside, as well as 1-O-β-D-glucopyranosylamplexine, boonein, 5-hydro-xymethylisochroman-1-one, 3-hydroxybenzyl β-D-glu-copyranoside, 8- O-primeverosylbellidifolin and 2-O-[α-L-rhamnopyranosyl-(1→2)-β-D-xylopyranosyl]-1,8-dihydroxy-6-methoxyxanthone. \\   S.japonica herb has been used as a stomachic or stimulant of appetite. Compounds found in the whole plant were the secoiridoid glycosides swertiajaposide A and swertiajaposide B, the unsaturated alcohol glycoside 3-butenyl 6'-O-α-L-arabinopyranosyl-β-D-glucopyranoside, the lignan glycoside 7R,7'R,8S,8'S-(+)-neo-olivil-4-O-β-D-glucopyranoside, as well as 1-O-β-D-glucopyranosylamplexine, boonein, 5-hydro-xymethylisochroman-1-one, 3-hydroxybenzyl β-D-glu-copyranoside, 8- O-primeverosylbellidifolin and 2-O-[α-L-rhamnopyranosyl-(1→2)-β-D-xylopyranosyl]-1,8-dihydroxy-6-methoxyxanthone. \\  
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 "Swertiamarin has similar pharmacological actions as 5-HT2 antagonist and 5-HT2C selective agonist. This warrants that swertiamarin might modulate 5-HT2 receptors rather than affecting the uptake of serotonin. In the light of present investigation, the mechanism of these drugs can correlate the role of central and peripheral 5-HT2 receptors in diabetes." \\ "Swertiamarin has similar pharmacological actions as 5-HT2 antagonist and 5-HT2C selective agonist. This warrants that swertiamarin might modulate 5-HT2 receptors rather than affecting the uptake of serotonin. In the light of present investigation, the mechanism of these drugs can correlate the role of central and peripheral 5-HT2 receptors in diabetes." \\
-[Role of 5-HT2 receptors in diabetes: swertiamarin seco-irioid glycoside might be a possible 5-HT2 receptor modulator., Sonawane, R.D., Deore, V.B., Patil, S.D., Patil, C.R., Surana, S.J., Goyal, R.K., Physiology & behavior, 2015, ]+[Role of 5-HT2 receptors in diabetes: swertiamarin seco-irioid glycoside might be a possible 5-HT2 receptor modulator., Sonawane, R.D., Deore, V.B., Patil, S.D., Patil, C.R., Surana, S.J., Goyal, R.K., Physiology & behavior, 2015]
  
 {{http://upload.wikimedia.org/wikipedia/ja/thumb/8/88/%E3%82%BB%E3%83%B3%E3%83%96%E3%83%AA_Swertia_japonica.JPG/640px-%E3%82%BB%E3%83%B3%E3%83%96%E3%83%AA_Swertia_japonica.JPG}} \\ {{http://upload.wikimedia.org/wikipedia/ja/thumb/8/88/%E3%82%BB%E3%83%B3%E3%83%96%E3%83%AA_Swertia_japonica.JPG/640px-%E3%82%BB%E3%83%B3%E3%83%96%E3%83%AA_Swertia_japonica.JPG}} \\
-picture source wikimedia commons, センブリ（千振、学名：Swertia japonica)+picture source wikimedia commons, センブリ（千振, Swertia japonica)
swertia_japonica_schult._makino.1426078407.txt.gz · Zuletzt geändert: 2015/03/11 13:53 von andreas

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