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Sideritis scardica Griseb. - Lamiaceae - ironwort, (Greek) mountain tea, Olympus tea, Griechischer Bergtee
„Sideritis scardica Griseb., Lamiaceae (ironwort, mountain tea), an endemic plant of the Balkan Peninsula, has been used in traditional medicine in the treatment of antimicrobial infections, gastrointestinal complaints, inflammation and rheumatic disorders… Aerial parts of “mountain tea” are traditionally known for their anti-inflammatory, anti-microbial, anti-bacterial, anti-rheumatic and gastroprotective properties. S. scardica is used as a loosening agent in bronchitis and bronchial asthma, against common cold and lung emphysema, as well…
According to the previously published data, in the Macedonian S. scardica essential oil, the most abundant compound was α-cadinol, whereas in the oil of Bulgarian origin the main components were diterpenic compounds and octadecanol (over 20%). In our sample, diterpenes constituted a significant percentage; with octadecanol representing only 0.21% in oil. The most abundant compounds were hexadecanoic acid, myristicin, menthol, caryophyllene oxide, and τ-muurolol (12.92, 5.23, 4.90, 4.84, and 3.62%, respectively).“
[Chemical and antimicrobial evaluation of supercritical and conventional Sideritis scardica Griseb., Lamiaceae extracts., Tadić, V., Bojović, D., Arsić, I., Đorđević, S., Aksentijevic, K., Stamenić, M., Janković, S., Molecules, Vol.17(3), 2012, 2683-2703]
http://www.mdpi.com/1420-3049/17/3/2683/pdf
„Sideritis scardiaca… extracts inhibited the uptake of all three monoamines into rat brain synaptosomes by their respective transporters, the alcoholic extracts being more effective than the water extract. EC50 values were in the range of 30–40 μg/ml. Inhibition of the human serotonin transporter by the methanol extract was even more effective (EC50 1.4 μg/ml)… The pharmacological profile of S. scardica extracts as triple monoamine reuptake inhibitors suggests their use in the phytochemical therapy of mental disorders associated with a malfunctioning monoaminergic neurotransmission, such as anxiety disorders, major depression, attention-deficit hyperactivity disorder, mental impairment or neurodegenerative diseases.“
[Extracts of Sideritis scardica as triple monoamine reuptake inhibitors., Knörle, R., Journal of Neural Transmission, Vol.119(12), 2012, 1477-1482]