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salvia_divinorum_epling_jativa [2019/04/29 10:17] andreas |
salvia_divinorum_epling_jativa [2019/04/29 10:22] (aktuell) andreas |
[Salvinorin A, an active component of the hallucinogenic sage Salvia divinorum is a highly efficacious κ-opioid receptor agonist: structural and functional considerations., Chavkin, C., Sud, S., Jin, W., Stewart, J., Zjawiony, J.K., Siebert, D.J., Roth, B.L., Journal of Pharmacology and Experimental Therapeutics, 308(3), 2004, 1197-1203] | [Salvinorin A, an active component of the hallucinogenic sage Salvia divinorum is a highly efficacious κ-opioid receptor agonist: structural and functional considerations., Chavkin, C., Sud, S., Jin, W., Stewart, J., Zjawiony, J.K., Siebert, D.J., Roth, B.L., Journal of Pharmacology and Experimental Therapeutics, 308(3), 2004, 1197-1203] |
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"Salvinorin-A led to a disconnection from external reality, induced elaborate visions and auditory phenomena, and modified interoception. The lower doses increased somatic sensations, but the highest dose led to a sense of a complete loss of contact with the body." \\ | "Salvinorin-A, the main psychoactive constituent in S. divinorum, is a non-nitrogenous neoclerodane diterpene with an affinity for the kappa opioid receptor (KOR; Roth et al., 2002). Despite its intense perception-modifying effects in humans, in vitro studies have shown that salvinorin-A does not bind to 5HT2A receptors, the molecular target of classic psychedelics like lysergic acid diethylamide (LSD), mescaline, psilocybin, and dimethyltryptamine (Roth et al., 2002; Prisinzano, 2005). ... \\ |
| Salvinorin-A led to a disconnection from external reality, induced elaborate visions and auditory phenomena, and modified interoception. The lower doses increased somatic sensations, but the highest dose led to a sense of a complete loss of contact with the body." \\ |
[Maqueda, Ana Elda, et al. "Salvinorin-A induces intense dissociative effects, blocking external sensory perception and modulating interoception and sense of body ownership in humans." International Journal of Neuropsychopharmacology 18.12 (2015): pyv065.] [[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4675976/]] | [Maqueda, Ana Elda, et al. "Salvinorin-A induces intense dissociative effects, blocking external sensory perception and modulating interoception and sense of body ownership in humans." International Journal of Neuropsychopharmacology 18.12 (2015): pyv065.] [[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4675976/]] |