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rosa_canina_l

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Rosa canina L. - Rosaceae - dog rose, common brier, dog brier, Hagebutte, Hunds-Rose, Hagrose

Deciduous spiny shrub, 1-3m high, native to Europe, Southwest Asia, Northwest Africa; introduced to North America and New Zealand; leaves odd-pinnate (5 or 7 leaflets); flowers solitary, pale pink.

Main volatile compounds found in the essential oil of rose hips of R.canina were vitispirane (10.3%), 5-methyl-3-hexanone and 2-heptanone (together 7.4%), β-ionone (5.4%), α-E-acaridial (5.1%), 6-Methyl-5-hepten-2-one (3.4%), and nonanal (2.5%).
[Chemical composition of hips essential oils of some Rosa L. species. Nowak, R., Z Naturforsch C, Vol.60(5-6), 2005, 369-378]
http://znaturforsch.com/ac/v60c/s60c0369.pdf?origin=publication_detail

The ethanolic extract of Rosa canina L. (Rosaceae) fruits was shown to possess significant inhibitory activity against inflammatory models (i.e., carrageenan-induced and PGE1-induced hind paw edema models, as well as on acetic acid-induced increase in a capillary permeability model) and on a pain model based on the inhibition of p-benzoquinone-induced writhing in mice. Hexane, chloroform, ethylacetate, n-butanol and the remaining water fractions were obtained through bioassay-guided fractionation. Ethylacetate and n-butanol fractions displayed potent anti-inflammatory and antinociceptive activities at a dose of 919 mg/kg without inducing acute toxicity. Further attempts to isolate and define the active constituent(s) were inconclusive, possibly due to the synergistic interaction of components in the extract.„
[In vivo anti-inflammatory and antinociceptive activity of the crude extract and fractions from Rosa canina L. fruits., Orhan, D.D., Hartevioğlu, A., Küpeli, E., Yesilada, E., Journal of ethnopharmacology, 112(2), 2007, 394-400]

“ While the water and methanol extracts were inactive in the COX-1, COX-2 and LTB4 inhibition assays, the n-hexane and the dichloromethane extracts inhibited all three enzymes. In the active extracts, the triterpenoic acids ursolic acid, oleanolic acid and betulinic acid were identified, although only in minute amounts. Furthermore, oleic, linoleic and α-linolenic acid were identified apart from several saturated fatty acids. Even though unsaturated fatty acids are known to be good inhibitors of COX-1, COX-2 and LT formation, no clear correlation between their concentration in the extracts and their activity was found. We suggest that other, yet unidentified, lipophilic constituents might play a more important role for the observed in vitro inhibitory activity on arachidonic acid metabolism. Some of the extracts also showed considerable DPPH radical scavenging activity, the methanolic extracts being most potent. The radical scavenging activity of the extracts correlated very well with their total phenolic content, while ascorbic acid contributes only little to the radical-scavenging activity due to its low concentration present in the extracts.„
[Phytochemical composition and in vitro pharmacological activity of two rose hip (Rosa canina L.) preparations., Wenzig, E.M., Widowitz, U., Kunert, O., Chrubasik, S., Bucar, F., Knauder, E., Bauer, R., Phytomedicine, 15(10), 2008, 826-835] http://www.sciencedirect.com/science/article/pii/S094471130800127X

The fruit flesh of rose hips from R.canina growing wild in Turkey contained large amounts of ascorbic acid (2,2%) and was very rich in potassium, calcium and magnesium.
[Variations in Chemical Compositions of Rosa damascena Mill. and Rosa canina L. Fruits. Kazaz, S., Baydar, H., Erbas, S., Czech J. Food Sci. Vol.27(3), 2009, 178-184]
http://www.sonerkazaz.com/wp-content/uploads/Variations-in-Chemical-Compositions-of-Rosa-damascena-Mill.-and-Rosa-canina-L.-Fruits.pdf

upload.wikimedia.org_wikipedia_commons_thumb_6_6a_illustration_rosa_canina0.jpg_640px-illustration_rosa_canina0.jpg
Thomé, O.W., Flora von Deutschland Österreich und der Schweiz, Tafeln, vol.3, t.415 (1885)
http://plantgenera.org/species.php?id_species=1260425

rosa_canina_l.1436106571.txt.gz · Zuletzt geändert: 2015/07/05 16:29 von andreas