Dies ist eine alte Version des Dokuments!
Rheum officinale Baill. - Polygonaceae
药用大黄 yao yong da huang (hin.), Chinese rhubarb, Canton rhubarb, Shensi rhubarb, Südchinesischer Rhabarber, Kanton-Rhabarber
Large perennial herb, 1.5-2m tall, native to Southwest China, Southeast Tibet, Birma; stem stout, hollow; leaf blades orbicular, 30-50 cm in diam., or longer than wide. http://www.efloras.org/florataxon.aspx?flora_id=2&taxon_id=200006743
The four major hydroxyanthraquinones from R.officinale are chrysophanol, emodin, physcion and aloe-emodin.
[Preparative isolation and purification of hydroxyanthraquinones from Rheum officinale Baill by high-speed counter-current chromatography using pH-modulated stepwise elution. Yang, F., Zhang, T., Tian, G., Cao, H., Liu, Q., Ito, Y., Journal of Chromatography A, Vol.858(1), 1999, 103-107]
„RK (raspberry ketone) from R. officinale inhibited melanogenesis through a post-transcriptional regulation of tyrosinase gene expression in cultured B16 melanoma cells. In addition, RK also inhibited melanogenesis of skin in both zebrafish and mice. Based on our findings reported here, RK would appear to have high potential for use in the cosmetics industry.“
[Evaluation of in vitro and in vivo depigmenting activity of raspberry ketone from Rheum officinale. Lin, V. C. H., Ding, H. Y., Kuo, S. Y., Chin, L. W., Wu, J. Y., Chang, T. S., International journal of molecular sciences, Vol.12(8), 2011, 4819-4835] http://www.mdpi.com/1422-0067/12/8/4819/htm
„… emodin may effectively delay the progression of airway inflammation and could be used as a therapy for patients with allergic airway inflammation.“
[Effects of an anthraquinone derivative from Rheum officinale Baill, emodin, on airway responses in a murine model of asthma. Chu, X., Wei, M., Yang, X., Cao, Q., Xie, X., Guan, M., Deng, X., Food and Chemical Toxicology, Vol.50(7), 2012, 2368-2375]
