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Piper fulvescens C.DC. - Piperaceae \\
yaguarundi (span., Paraguay)

Evergreen shrub, 1-1.5m high, nativer to Paraguay; laeves ovate, heart-shaped at the base; flowers white. \\
[[http://www.qui.una.py/botanicafcq/Vol%204%20%281%29%201997/Anatomia%20Foliar_Ortiz%202.pdf]]

"The essential oil from the leaves of the aromatic aniseed smelling plant Piper fulvescens, obtained by hydrodistillation, was investigated by GC and GC–MS, as well as by 13C-NMR after fractionation of the oil by column chromatography. A total of 37 constituents, representing 78.2% of the oil were identified. The main compounds were trans-anethole (26.4%) and [[http://webbook.nist.gov/cgi/inchi/InChI%3D1S/C15H24/c1-10-5-4-6-15-8-12-11%287-14%2810,15%293%2913%2812,2%299-15/h10-12H,4-9H2,1-3H3|ishwarane]] (12.1%), an unusual sesquiterpene hydrocarbon." \\
[Chemical composition of the essential oil from the leaves of //Piper fulvescens//, a plant traditionally used in Paraguay. Vila, Roser, et al. Journal of ethnopharmacology, Vol.76.1, 2001, 105-107]

"Activity-guided fractionation of the dichloromethane extract from leaves of Piper fulvescens, using an agar overlay bioautographic method, led to the isolation of three antifungal neolignans identified as [[http://www.chemfaces.com/natural/Conocarpan-CFN98208.html|conocarpan]], eupomatenoid 5 and eupomatenoid 6. The minimal inhibitory concentration of these three neolignans against five fungi strains were determined. Conocarpan showed the widest activity, whereas eupomatenoid 6 was the most active against dermatophytes." \\
[Antifungal principles from Piper fulvescens. Freixa B, Vila R, Ferro EA, Adzet T, Cañigueral S., Planta Med. Vol.67(9), 2001, 873-5]

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