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nerium_oleander_l

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Nerium oleander L. - Apocynaceae - oleander, rose-bay, Oleander, Rosenlorbeer

Evergreen subshrub, native to the Mediterranean, East Asia, cultivated worldwide as ornamental; leaves narrowly elliptiv, leathery; flowers fragrant, white, salmon, pink or purplish red. „All parts of the plant are extremely toxic. The seed-oil content is up to 58.5%.“
http://www.efloras.org/florataxon.aspx?flora_id=2&taxon_id=200018424

Toxic principle in all parts of the plant are cardenolides as monoglycosides, which are also CNS depressant.
http://ijpsr.com/V1I3/3Vol%201%20Issue%203%20Review%203.pdf

„A 37-year-old man presented two hours after the ingestion of “a handful” of oleander leaves (probably Nerium oleander) in a suicide attempt. Cardiotoxicity was evidenced by the presence of bradycardia (rate, 30 to 45) with sinoatrial nodal arrest and junctional escape consistent with a cardiac glycoside effect. The patient was treated empirically with a single dose of five vials (200 mg) of digoxin-specific Fab antibody fragments (Digibind®). The pretreatment digoxin level was 1.5 ng/mL. After treatment, the patient's rhythm stabilized with residual sinus bradycardia (rate, 56). The patient recovered uneventfully and was discharged on the fifth hospital day to inpatient psychiatric care.“
[Oleander poisoning: treatment with digoxin-specific Fab antibody fragments., Shumaik, G. M., Wu, A. W., Ping, A. C.,Annals of emergency medicine, Vol.17(7), 1988, 732-735]

upload.wikimedia.org_wikipedia_commons_2_2d_nerium_oleander_blanco1.37.jpg

nerium_oleander_l.1417435703.txt.gz · Zuletzt geändert: 2014/12/01 12:08 von andreas

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