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momordica_charantia_l [2016/01/18 11:05]
andreas
momordica_charantia_l [2016/01/18 12:21] (aktuell)
andreas
Zeile 6: Zeile 6:
 "The fruit is most often eaten green, or as it is beginning to turn yellow. At this stage, the fruit's flesh is crunchy and watery in texture, similar to cucumber, chayote or green bell pepper, but bitter. The skin is tender and edible. Seeds and pith appear white in unripe fruits; they are not intensely bitter and can be removed before cooking." [[https://en.wikipedia.org/wiki/Momordica_charantia]] "The fruit is most often eaten green, or as it is beginning to turn yellow. At this stage, the fruit's flesh is crunchy and watery in texture, similar to cucumber, chayote or green bell pepper, but bitter. The skin is tender and edible. Seeds and pith appear white in unripe fruits; they are not intensely bitter and can be removed before cooking." [[https://en.wikipedia.org/wiki/Momordica_charantia]]
  
-The plant contains the glucosides of sitosterole and 5alpha,25-stigmasterol, a mixture known as charantin. Charantin was found in dried fruit (55.2mg/g d.w.) and leaf (144.5mg/g d.w.) samples of bitter melon. \\ +The plant contains the glucosides of β-sitosterol and ,25-stigmastadiene-3β-ol, a (1:1) mixture known as charantin (without hypoglycemic effect, see Sucrow). Charantin was found in dried fruit (55.2mg/g d.w.) and leaf (144.5mg/g d.w.) samples of bitter melon. \\ 
-[Medicinal plants in tropical West Africa., Oliver-BeverBepCambridge University Press1986] \\+[Über Steringlucoside und ein neues stigmastadienol aus momordica charantia., SucrowW.Tetrahedron letters6(26), 1965, 2217-2221] \\
 [Extraction of insulin like compounds from bitter melon plants., El-Said, S.M., Al-Barak, A.S., Am. J. Drug Discovery Dev, 1, 1-7, 2011] [Extraction of insulin like compounds from bitter melon plants., El-Said, S.M., Al-Barak, A.S., Am. J. Drug Discovery Dev, 1, 1-7, 2011]
  
-"Bioguided fractionation of the methanol extract of Momordica charantia dried gourds led to the isolation of cucurbitane triterpenoids... in order to evaluate the contribution of the cucurbitane triterpenoids of the ether fraction of M. charantia methanol extract to in vivo anti-diabetic effects, the major compounds, 5β,19-epoxy-3β,25-dihydroxycucurbita-6,23(E)-diene, and 3β,7β,25-trihydroxycucurbita-5,23(E)-dien-19-al have been tested and have shown blood hypoglycaemic effects in the diabetes-induced male ddY mice strain at 400 mg/kg. The two aglycones of charantin did not show any hypoglycaemic effects. Our finding is the first demonstration that major pure cucurbutanoid compounds of M. charantia have in vivo hypoglycaemic effects." \\+"Bioguided fractionation of the methanol extract of Momordica charantia dried gourds led to the isolation of [[https://en.wikipedia.org/wiki/Cucurbitane|cucurbitane]] triterpenoids... in order to evaluate the contribution of the cucurbitane triterpenoids of the ether fraction of M. charantia methanol extract to in vivo anti-diabetic effects, the major compounds, 5β,19-epoxy-3β,25-dihydroxycucurbita-6,23(E)-diene, and 3β,7β,25-trihydroxycucurbita-5,23(E)-dien-19-al have been tested and have shown blood hypoglycaemic effects in the diabetes-induced male ddY mice strain at 400 mg/kg. The two aglycones of charantin did not show any hypoglycaemic effects. Our finding is the first demonstration that major pure cucurbutanoid compounds of M. charantia have in vivo hypoglycaemic effects." \\
 [Momordica charantia constituents and antidiabetic screening of the isolated major compounds., Harinantenaina, L., Tanaka, M., Takaoka, S., Oda, M., Mogami, O., Uchida, M., Asakawa, Y., Chemical and Pharmaceutical Bulletin, 54(7), 2006, 1017-1021]  [Momordica charantia constituents and antidiabetic screening of the isolated major compounds., Harinantenaina, L., Tanaka, M., Takaoka, S., Oda, M., Mogami, O., Uchida, M., Asakawa, Y., Chemical and Pharmaceutical Bulletin, 54(7), 2006, 1017-1021] 
  
Zeile 16: Zeile 16:
 [Momordica charantia for type 2 diabetes mellitus., Ooi, C.P., Yassin, Z., Hamid, T.A., The Cochrane Library, 2012] [[http://www.update-software.com/BCP/WileyPDF/EN/CD007845.pdf]] [Momordica charantia for type 2 diabetes mellitus., Ooi, C.P., Yassin, Z., Hamid, T.A., The Cochrane Library, 2012] [[http://www.update-software.com/BCP/WileyPDF/EN/CD007845.pdf]]
  
-{{:momordica_charantia_001.jpg?700}}\\+{{:momordica_charantia.jpg?500}} \\ 
 +Houtte, L. van, Flore des serres et des jardin de l’Europe, vol.10 p.193, t.1047 (1855) \\ 
 +[[http://plantgenera.org/species.php?id_species=677214]] 
 + 
 +{{:momordica_charantia_001.jpg?500}}\\
 Momordica charantia [[https://creativecommons.org/licenses/by-sa/3.0/de/|CC BY-SA 3.0]] author: H. Zell  \\ [[https://commons.wikimedia.org/wiki/File:Momordica_charantia_001.JPG#/media/File:Momordica_charantia_001.JPG]] Momordica charantia [[https://creativecommons.org/licenses/by-sa/3.0/de/|CC BY-SA 3.0]] author: H. Zell  \\ [[https://commons.wikimedia.org/wiki/File:Momordica_charantia_001.JPG#/media/File:Momordica_charantia_001.JPG]]
momordica_charantia_l.1453111551.txt.gz · Zuletzt geändert: 2016/01/18 11:05 von andreas