Beide Seiten der vorigen Revision
Vorhergehende Überarbeitung
Nächste Überarbeitung
|
Vorhergehende Überarbeitung
|
melilotus_officinalis_l._lam [2015/07/11 16:09] andreas |
melilotus_officinalis_l._lam [2023/06/30 14:27] (aktuell) andreas |
[[http://www.efloras.org/florataxon.aspx?flora_id=2&taxon_id=200012219]] | [[http://www.efloras.org/florataxon.aspx?flora_id=2&taxon_id=200012219]] |
| |
"Extracts are used to treat the symptoms of venous and lymphatic insuffiency and capillary fragility, such as varicose veins, pruritus, cramp in the calf and in acute attacks of haemorrhoids... [[https://en.wikipedia.org/wiki/Coumarin|Coumarin]] shows anti-oedemic and anti-exudative activities and accelerates wound-healing. It increases the flow rate in veins (and the lymph system) and decreases capillary permeability but has no anticoagulant properties." \\ | "Extracts are used to treat the symptoms of venous and lymphatic insuffiency and capillary fragility, such as varicose veins, pruritus, cramp in the calf and in acute attacks of haemorrhoids... [[https://en.wikipedia.org/wiki/Coumarin|Coumarin]] shows anti-oedemic and anti-exudative activities and accelerates wound-healing. It increases the flow rate in veins (and the lymph system) and decreases capillary permeability but has no anticoagulant properties." [Medicinal Plants of the World. Ben-Erik Van Wyk and Michael Wink, Pretoria 2004, 203] \\ |
[Medicinal Plants of the World. Ben-Erik Van Wyk and Michael Wink, Pretoria 2004, 203] | (for cumarin toxicology, see also [[galium_odoratum_l._scop|Galium odoratum]]) |
| |
{{:coumarin.jpg|}} coumarin | |
| |
In living plants, coumarin is glycosidically bound as melilotoside, an odorless precursor. On wilting or injuring, o-coumaric acid (o-hydroxy-trans-cinnamic acid) is released from the glucoside; o-trans-coumaric acid is in equilibrium with the cis-coumaric acid, which then spontaneously lactonizes to coumarin. Coumarin is the aroma impact compound of wilted or dried M.officinalis. \\ | In living plants, coumarin is glycosidically bound as melilotoside, an odorless precursor. On wilting or injuring, o-coumaric acid (o-hydroxy-trans-cinnamic acid) is released from the glucoside; o-trans-coumaric acid is in equilibrium with the cis-coumaric acid, which then spontaneously lactonizes to coumarin. Coumarin is the aroma impact compound of wilted or dried M.officinalis. \\ |
[Hagers Handbuch der Pharmazeutischen Praxis, Springer 2010] | [Hagers Handbuch der Pharmazeutischen Praxis, Springer 2010] |
| |
Coumarin alone made up more than 89% of all volatiles collected from M.officinalis. An extract obtained by solid-liquid extraction of dry sweet clover herb could be fractionated to identify minor volatile components. Higher proportions of coumarin derivatives such as 3,4-dihydrocoumarin, dihydrocoumarin methyl and ethyl ester could be found. Other minor components are anethol, 4-methoxy benzaldehyde (anisaldehyde), 2-hexadecanone, and cresol eg.; γ-pentadecalactone was regarded as species indicator compound among the 84 components identified from M.officinale volatiles. \\ [Volatile constituents of sweet clover (Melilotus officinalis L. Lam.)., Wörner, M., Schreier, P., Zeitschrift für Lebensmittel-Untersuchung und Forschung, Vol.190(5), 1990, 425-428] | |{{:coumarin.jpg|coumarin}} \\ coumarin |{{anisaldehyde.jpg| anisaldehyde.jpg}} \\ anisaldehyde |{{anethol.jpg| (E)-anethole}} \\ (E)-anethole | |
| |
| Coumarin alone made up more than 89% of all volatiles collected from M.officinalis. An extract obtained by solid-liquid extraction of dry sweet clover herb could be fractionated to identify minor volatile components. Higher proportions of coumarin derivatives such as 3,4-dihydrocoumarin, dihydrocoumaric acid methyl and ethyl ester could be found. Other minor components are anethol, 4-methoxy benzaldehyde (anisaldehyde), 2-hexadecanone, and cresol eg.; γ-pentadecalactone was regarded as species indicator compound among the 84 components identified from M.officinale volatiles. \\ [Volatile constituents of sweet clover (Melilotus officinalis L. Lam.)., Wörner, M., Schreier, P., Zeitschrift für Lebensmittel-Untersuchung und Forschung, Vol.190(5), 1990, 425-428] |
| |
HPLC of an ethanolic extract prepared from air-dried leaves of M.offcinalis revealed 18 phenolic compounds, predominantly representing coumarins, flavonoids, and derivatives of phenolocarboxylic acids. Main components were ferulic acid (25.0%), arbutin (14.9%), caffeic acid (12.5%), chlorogenic acid (6.8%), rutin (6.2%), hyperoside (5.8%), cinnamic acid (4.6%), coumarin (3.8%). Minor constituents were hesperidin (2.0%), vitexin (1.3%), 4-oxycoumarin (0.15%), and luteolin (0.03%). \\ | HPLC of an ethanolic extract prepared from air-dried leaves of M.offcinalis revealed 18 phenolic compounds, predominantly representing coumarins, flavonoids, and derivatives of phenolocarboxylic acids. Main components were ferulic acid (25.0%), arbutin (14.9%), caffeic acid (12.5%), chlorogenic acid (6.8%), rutin (6.2%), hyperoside (5.8%), cinnamic acid (4.6%), coumarin (3.8%). Minor constituents were hesperidin (2.0%), vitexin (1.3%), 4-oxycoumarin (0.15%), and luteolin (0.03%). \\ |
[[http://plantgenera.org/species.php?id_species=655188]] | [[http://plantgenera.org/species.php?id_species=655188]] |
| |
{{:melilotus_officinalis_r.jpg?600}} | {{:melilotus_officinalis_r.jpg}} \\ |
| Melilotus officinalis, [[https://creativecommons.org/licenses/by-sa/3.0/de/|CC BY-SA 3.0]], Author: Andreas Kraska |