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melilotus_officinalis_l._lam [2015/01/29 12:03]
andreas
melilotus_officinalis_l._lam [2023/06/30 14:27] (aktuell)
andreas
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 [[http://www.efloras.org/florataxon.aspx?flora_id=2&taxon_id=200012219]] [[http://www.efloras.org/florataxon.aspx?flora_id=2&taxon_id=200012219]]
  
-"Extracts are used to treat the symptoms of venous and lymphatic insuffiency and capillary fragility, such as varicose veins, pruritus, cramp in the calf and in acute attacks of haemorrhoids... [[https://en.wikipedia.org/wiki/Coumarin|Coumarin]] shows anti-oedemic and anti-exudative activities and accelerates wound-healing. It increases the flow rate in veins (and the lymph system) and decreases capillary permeability but has no anticoagulant properties." \\ +"Extracts are used to treat the symptoms of venous and lymphatic insuffiency and capillary fragility, such as varicose veins, pruritus, cramp in the calf and in acute attacks of haemorrhoids... [[https://en.wikipedia.org/wiki/Coumarin|Coumarin]] shows anti-oedemic and anti-exudative activities and accelerates wound-healing. It increases the flow rate in veins (and the lymph system) and decreases capillary permeability but has no anticoagulant properties." [Medicinal Plants of the World. Ben-Erik Van Wyk and Michael Wink, Pretoria 2004, 203] \\ 
-[Medicinal Plants of the World. Ben-Erik Van Wyk and Michael Wink, Pretoria 2004, 203]+(for cumarin toxicology, see also [[galium_odoratum_l._scop|Galium odoratum]]) 
  
 In living plants, coumarin is glycosidically bound as melilotoside, an odorless precursor. On wilting or injuring, o-coumaric acid (o-hydroxy-trans-cinnamic acid) is released from the glucoside; o-trans-coumaric acid is in equilibrium with the cis-coumaric acid, which then spontaneously lactonizes to coumarin. Coumarin is the aroma impact compound of wilted or dried M.officinalis. \\ In living plants, coumarin is glycosidically bound as melilotoside, an odorless precursor. On wilting or injuring, o-coumaric acid (o-hydroxy-trans-cinnamic acid) is released from the glucoside; o-trans-coumaric acid is in equilibrium with the cis-coumaric acid, which then spontaneously lactonizes to coumarin. Coumarin is the aroma impact compound of wilted or dried M.officinalis. \\
 [Hagers Handbuch der Pharmazeutischen Praxis, Springer 2010] [Hagers Handbuch der Pharmazeutischen Praxis, Springer 2010]
  
-Coumarin alone made up more than 89% of all volatiles collected from M.officinalis. An extract obtained by solid-liquid extraction of dry sweet clover herb could be fractionated to identify minor volatile components. Higher proportions of coumarin derivatives such as 3,4-dihydrocoumarin, dihydrocoumarin methyl and ethyl ester could be found. Other minor components are anethol, 4-methoxy benzaldehyde (anisaldehyde), 2-hexadecanone, and cresol eg.; γ-pentadecalactone was regarded as species indicator compound among the 84 components identified from M.officinale volatiles. \\ [Volatile constituents of sweet clover (Melilotus officinalis L. Lam.)., Wörner, M., Schreier, P., Zeitschrift für Lebensmittel-Untersuchung und Forschung, Vol.190(5), 1990, 425-428]+|{{:coumarin.jpg|coumarin}}  \\ coumarin |{{anisaldehyde.jpg| anisaldehyde.jpg}} \\ anisaldehyde |{{anethol.jpg| (E)-anethole}} \\ (E)-anethole | 
 + 
 +Coumarin alone made up more than 89% of all volatiles collected from M.officinalis. An extract obtained by solid-liquid extraction of dry sweet clover herb could be fractionated to identify minor volatile components. Higher proportions of coumarin derivatives such as 3,4-dihydrocoumarin, dihydrocoumaric acid methyl and ethyl ester could be found. Other minor components are anethol, 4-methoxy benzaldehyde (anisaldehyde), 2-hexadecanone, and cresol eg.; γ-pentadecalactone was regarded as species indicator compound among the 84 components identified from M.officinale volatiles. \\ [Volatile constituents of sweet clover (Melilotus officinalis L. Lam.)., Wörner, M., Schreier, P., Zeitschrift für Lebensmittel-Untersuchung und Forschung, Vol.190(5), 1990, 425-428]
  
 HPLC of an ethanolic extract prepared from air-dried leaves of M.offcinalis revealed 18 phenolic compounds, predominantly representing coumarins, flavonoids, and derivatives of phenolocarboxylic acids. Main components were ferulic acid (25.0%), arbutin (14.9%), caffeic acid (12.5%), chlorogenic acid (6.8%), rutin (6.2%), hyperoside (5.8%), cinnamic acid (4.6%), coumarin (3.8%). Minor constituents were hesperidin (2.0%), vitexin (1.3%), 4-oxycoumarin (0.15%), and luteolin (0.03%). \\ HPLC of an ethanolic extract prepared from air-dried leaves of M.offcinalis revealed 18 phenolic compounds, predominantly representing coumarins, flavonoids, and derivatives of phenolocarboxylic acids. Main components were ferulic acid (25.0%), arbutin (14.9%), caffeic acid (12.5%), chlorogenic acid (6.8%), rutin (6.2%), hyperoside (5.8%), cinnamic acid (4.6%), coumarin (3.8%). Minor constituents were hesperidin (2.0%), vitexin (1.3%), 4-oxycoumarin (0.15%), and luteolin (0.03%). \\
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 [Chemical composition of the leaves essential oil of Melilotus officinalis (L.) pallas from colombia., Quijano-Celis, C.E., Pino, J.A., Morales, G., Journal of Essential Oil Bearing Plants, Vol.13(3), 2010, 313-315] [Chemical composition of the leaves essential oil of Melilotus officinalis (L.) pallas from colombia., Quijano-Celis, C.E., Pino, J.A., Morales, G., Journal of Essential Oil Bearing Plants, Vol.13(3), 2010, 313-315]
  
-{{http://upload.wikimedia.org/wikipedia/commons/3/34/Melilotus_officinalis_-_K%C3%B6hler%E2%80%93s_Medizinal-Pflanzen-093.jpg}}+{{:melilotus_officinalis_d.jpg?500}} \\ 
 +Thomé,O.W., Flora von Deutschland Österreich und der Schweiz, Tafeln, vol.3 t.432 (1885) \\ 
 +[[http://plantgenera.org/species.php?id_species=655188]] 
 + 
 +{{:melilotus_officinalis_r.jpg}} \\ 
 +Melilotus officinalis, [[https://creativecommons.org/licenses/by-sa/3.0/de/|CC BY-SA 3.0]], Author: Andreas Kraska
melilotus_officinalis_l._lam.1422529389.txt.gz · Zuletzt geändert: 2015/01/29 12:03 von andreas