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justicia_adhatoda_l
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| Beide Seiten der vorigen Revision Vorhergehende Überarbeitung Nächste Überarbeitung | Vorhergehende Überarbeitung | ||
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justicia_adhatoda_l [2015/11/17 15:13] andreas |
justicia_adhatoda_l [2018/03/12 10:24] andreas |
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| Evergreen dense shrub of northern India, naturalized in India, Sri Lanka, Southeast Asia, up to 2.5m high, with unpleasant smell; stem bark yellowish; leaves simple, petioled, lanceolate to elliptic, entire; white flowers in axillary spikes; spikes with long peduncles; fruit a 4-seeded capsule, 2-2.5cm long, seeds 5-7mm in diameter. | Evergreen dense shrub of northern India, naturalized in India, Sri Lanka, Southeast Asia, up to 2.5m high, with unpleasant smell; stem bark yellowish; leaves simple, petioled, lanceolate to elliptic, entire; white flowers in axillary spikes; spikes with long peduncles; fruit a 4-seeded capsule, 2-2.5cm long, seeds 5-7mm in diameter. | ||
| - | "The original home is the Himalayan region | + | "This shrub has a number |
| The leaves contain the quinazoline alkaloids deoxyvasicine, | The leaves contain the quinazoline alkaloids deoxyvasicine, | ||
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| "... even at the highest clinically used doses ambroxol does not have significant direct effects on the CNS. At clinically relevant plasma concentrations ambroxol either does not penetrate blood-brain barrier, or its brain levels are too low to cause relevant effects. \\ | "... even at the highest clinically used doses ambroxol does not have significant direct effects on the CNS. At clinically relevant plasma concentrations ambroxol either does not penetrate blood-brain barrier, or its brain levels are too low to cause relevant effects. \\ | ||
| - | Ambroxol has been used in the therapy of airway diseases since late 1970s. Its history can be traced, however, to ayurvedic medicine in ancient India. The plant Adhatoda vasica has been used in India for similar indications for centuries. In Germany this plant is still called ‘Indisches Lungenkraut’ (Indian lung weed). The likely active substance in the plant is the alkaloid, vasicine. A chemically related drug, bromhexine, was introduced in 1965 to treat mild respiratory disorders. Ambroxol, the active metabolite of bromexine, has been found to be responsible for the therapeutic effect; and found to be superior to bromhexine in its pharmacokinetics, | + | Ambroxol has been used in the therapy of airway diseases since late 1970s. Its history can be traced, however, to ayurvedic medicine in ancient India. The plant Adhatoda vasica has been used in India for similar indications for centuries. In Germany this plant is still called ‘Indisches Lungenkraut’ (Indian lung weed). The likely active substance in the plant is the alkaloid, vasicine. A chemically related drug, bromhexine, was introduced in 1965 to treat mild respiratory disorders. Ambroxol, the active metabolite of bromhexine, has been found to be responsible for the therapeutic effect; and found to be superior to bromhexine in its pharmacokinetics, |
| [Ambroxol: a CNS drug?., Weiser, T., CNS neuroscience & therapeutics, | [Ambroxol: a CNS drug?., Weiser, T., CNS neuroscience & therapeutics, | ||
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| [[http:// | [[http:// | ||
| - | {{: | + | {{: |
| Curtis’s Botanical Magazine, vol.22 t.861 (1805) [S.T.Edwards] \\ | Curtis’s Botanical Magazine, vol.22 t.861 (1805) [S.T.Edwards] \\ | ||
| [[http:// | [[http:// | ||
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| + | {{: | ||
| + | Jusiticia adhatoda, Funchal Botanic Gardens, Andreas Kraska (2018) [[https:// | ||
justicia_adhatoda_l.txt · Zuletzt geändert: 2018/03/12 10:24 von andreas
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