"The essential oil of Alaska cedar heartwood is known to contain compounds which contribute to the remarkable durability of this species. While previous research has identified several compounds, a complete description of this oil, which has a "burnt-grape fruit" odor, has not been undertaken. In this research a profile of the oil is given in which the major components are identified by GC-MS, isolation and spectroscopic techniques. The major components of the steam distilled essential oil were identified as nootkatin, nootkatone, valencene, nootaktene, carvacrol, methyl carvacrol, nootkatol, and eremophil-1(10),11-dien-13-ol. In addition, it was found that the diethyl ether extract of the heartwood contained 1(10)-eremophilen-11,12-epoxide as a major component in addition to the compounds found in the steam distilled essential oil. 1(10)-Eremophilen-11,12-epoxide apparently does not survive the condition of steam distillation. Nootkatol, eremophil-1(10),11-dien-13-ol and 1(10)-eremophilen-11,12-epoxide have not been previously reported in Alaska cedar. Nootkatol is a known compound having been reported in other plants. However, eremophil-1(10),11-dien-13-ol and 1(10)-eremophilen-11,12-epoxide represent new chemical structures to science being described here for the first time." \\ | "The essential oil of Alaska cedar heartwood is known to contain compounds which contribute to the remarkable durability of this species. While previous research has identified several compounds, a complete description of this oil, which has a "burnt-grape fruit" odor, has not been undertaken. In this research a profile of the oil is given in which the major components are identified by GC-MS, isolation and spectroscopic techniques. The major components of the steam distilled essential oil were identified as nootkatin, nootkatone, valencene, nootaktene, carvacrol, methyl carvacrol, nootkatol, and eremophil-1(10),11-dien-13-ol. In addition, it was found that the diethyl ether extract of the heartwood contained 1(10)-eremophilen-11,12-epoxide as a major component in addition to the compounds found in the steam distilled essential oil. 1(10)-Eremophilen-11,12-epoxide apparently does not survive the condition of steam distillation. Nootkatol, eremophil-1(10),11-dien-13-ol and 1(10)-eremophilen-11,12-epoxide have not been previously reported in Alaska cedar. Nootkatol is a known compound having been reported in other plants. However, eremophil-1(10),11-dien-13-ol and 1(10)-eremophilen-11,12-epoxide represent new chemical structures to science being described here for the first time." \\ |
Essential oil components extracted from the heartwood of Chamaecyparis nootkatensis were evaluated against nymphal Ixodes scapularis in a laboratory bioassay and compared with N,N-diethyl-3-methylbenzamide (DEET). Nootkatone, valencene-13-ol, nootkatone 1→10 epoxide, and carvacrol had repellent concentration (RC)50 values in the range of DEET. \\ | Essential oil components extracted from the heartwood of Chamaecyparis nootkatensis were evaluated against nymphal Ixodes scapularis in a laboratory bioassay and compared with N,N-diethyl-3-methylbenzamide (DEET). Nootkatone, valencene-13-ol, nootkatone 1→10 epoxide, and carvacrol had repellent concentration (RC)50 values in the range of DEET. \\ |