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copaifera_langsdorffii_desf [2017/04/25 08:50] andreas |
copaifera_langsdorffii_desf [2017/12/21 15:09] (aktuell) andreas |
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"GC/MS analysis of the hydrodistilled essential oils from leaves, root bark, fruit peel, trunk bark, trunk wood, root wood and fruits of Copaifera langsdorffii Desf. obtained in 0.04%, 0.01%, 0.7%, 0.003%, 0.008%, 0.07% and 0.3% yield, respectively, | "GC/MS analysis of the hydrodistilled essential oils from leaves, root bark, fruit peel, trunk bark, trunk wood, root wood and fruits of Copaifera langsdorffii Desf. obtained in 0.04%, 0.01%, 0.7%, 0.003%, 0.008%, 0.07% and 0.3% yield, respectively, | ||
[Volatile constituents of Copaifera langsdorffii from the Brazilian northeast. | [Volatile constituents of Copaifera langsdorffii from the Brazilian northeast. | ||
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+ | "A number of studies have shown that CB2 is critically involved in the modulation of inflammatory and neuropathic pain responses. In this study, we have investigated the analgesic effects of BCP [**β-caryophyllene**] in animal models of inflammatory and neuropathic pain. We demonstrate that orally administered BCP reduced inflammatory (late phase) pain responses in the formalin test in a CB2 receptor-dependent manner, while it had no effect on acute (early phase) responses. In a neuropathic pain model the chronic oral administration of BCP attenuated thermal hyperalgesia and mechanical allodynia, and reduced spinal neuroinflammation. Importantly, | ||
+ | [Klauke, A-L., et al. "The cannabinoid CB 2 receptor-selective phytocannabinoid beta-caryophyllene exerts analgesic effects in mouse models of inflammatory and neuropathic pain." European Neuropsychopharmacology 24.4 (2014): 608-620] [[http:// | ||
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