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--- cetraria_islandica_l._ach [2015/09/26 17:01]
andreas
+++ cetraria_islandica_l._ach [2015/09/27 10:01]
andreas
@@ Zeile 8: / Zeile 8: @@
 Pharmaceutical preparations containing extracts of Iceland moss are used to treat hoarseness and dryness of the mucosa of mouth and throat, pharyngitis, laryngitis, and dry cough in acute and chronic bronchitis.
-Polyketide synthesis in C.islandica leads to protocetraric acid, fumarprotocetraric acid, confumarprotocetraric acid, succin-protocetraric acid (protolichesterinic acid). Lichens produce also polysaccharides in considerable amounts. " ... lichen glucans are linear polymers of glucosyl units connected by a variety of O-glycosidic linkages and are classified into β-glucans... Lichenan is a cold-water-insoluble, linear (1->3)-(1->4)-β-glucan with a linkage ratio of 3:7 and was the first polysaccharide isolated from a lichen species (Cetraria islandica) in 1815 by Berzelius..." \\
+Polyketide synthesis in C.islandica leads to protocetraric acid, fumarprotocetraric acid, confumarprotocetraric acid, succin-protocetraric acid (protolichesterinic acid). Lichens produce also polysaccharides in considerable amounts. " ... lichen glucans are linear polymers of glucosyl units connected by a variety of O-glycosidic linkages and are classified into β-glucans (lichenan, pustulan, laminaran, and branched β-glucan) and α-glucans (isolichenan, nigeran, and pullulan). ... Lichenan is a cold-water-insoluble, linear (1->3)-(1->4)-β-glucan with a linkage ratio of 3:7 and was the first polysaccharide isolated from a lichen species (Cetraria islandica) in 1815 by Berzelius..." \\
 [Accumulation of Potential Pharmaceutically Relevant Lichen Metabolites in Lichens and Cultured Lichen Symbionts., Iacomini, M., Studies in Natural Products Chemistry, 2013, 337-380]
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-From Iceland moss, Cetraria islandica (L.) Ach. a polysaccharide with pronounced immunostimulating activity in an in vitro phagocytosis assay and in the in in vivo carbon clearance assay was isolated. It is a branched galactomannan with a backbone composed of two structural elements: (1->6)-linked alpha-D-mannopyranosyl and alpha-D-(1->6)-galactopyranosyl units. \\
+From Iceland moss, Cetraria islandica (L.) Ach. a polysaccharide with pronounced immunostimulating activity in an in vitro phagocytosis assay and in the in in vivo carbon clearance assay was isolated. It is a branched galactomannan with a backbone composed of two structural elements: (1->6)-linked α-D-mannopyranosyl and α-D-(1->6)-galactopyranosyl units. \\
 [Immunologically active polysaccharide from Cetraria islandica., Ingolfsdottir, K., Jurcic, K., Fischer, B., Wagner, H., Planta medica, 60(6), 1994, 527-531]

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