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Brucea javanica (L.) Merr. - syn.Brucea amarissima (Lour.) Desv. ex Gomes; Rhus javanica L. - Simaroubaceae
Java brucea, kosam seed, Macassar kernels
Shrub or small tree, up to 3m high, native to Southeast Asia (India to Papua New Guinea); leaves imparipinnate, leaflets 5-11, oval-lanceolate, serrate, densely pubescent, especially the underside; flowers minute, purple, in numerous small cymes or clusters collected into axillary panicles; fruit and drupe ovoid, black when ripe; seeds blackish brown.
http://www.asianplant.net/Simaroubaceae/Brucea_javanica.htm
„A microdilution technique for the assessment of in vitro activity against Entamoeba histolytica was devised and validated with metronidazole. The test was used to detect the antiamoebic activities of plant extracts prepared from the traditional remedies Brucea javanica fruits and Simarouba amara stems. The activity was associated with quassinoid-containing fractions. The 50% inhibitory concentrations for some quassinoids against amoebae were determined by using the microdilution method. These concentrations ranged from 0.019 micrograms.ml-1 for bruceantin, the most active quassinoid, to greater than 5 micrograms.ml-1 for glaucarubol, the least active compound tested.“
[Use of microdilution to assess in vitro antiamoebic activities of Brucea javanica fruits, Simarouba amara stem, and a number of quassinoids., Wright, C.W., O'Neill, M.J., Phillipson, J.D., Warhurst, D.C., Antimicrobial agents and chemotherapy, Vol.32(11), 1988, 1725-1729]
Flora Malesiana, vol.6(2), p.210, fig.12 a-d (1962) [R.van Crevel]
http://plantgenera.org/species.php?id_species=160807