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asarum_sieboldii_miq

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asarum_sieboldii_miq [2015/07/02 08:02]
andreas
asarum_sieboldii_miq [2015/12/22 07:41]
andreas
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 [Hager; Fujita Y, Bot.Mag.Tokyo, 79, (1966), 783-790]  [Hager; Fujita Y, Bot.Mag.Tokyo, 79, (1966), 783-790] 
  
-"The methanolic extract of the roots of Asiasarum sieboldi has been evaluated for anti-allergic effects on various experimental models in vitro and in vivo. Bioassay-guided fractionation of the methanolic extract resulted in isolation of suppressive compounds in the PCA test: methyleugenol (1), elemicin (2), gamma-asarone (3), (-)-asarinin (4), and (-)-sesamin (5). Furthermore, elemicin (2) and (2E,4E,8Z,10E)-N-isobutyl-2,4,8,10-dodecatetraenami de (6) were found to exhibit an inhibitory action on 5-lipoxygenase (5-LOX) from RBL-1 cells. 3',4'-Dimethoxycinnamaldehyde (7) and xanthoxylol (8) potently reduced the contractile response of guinea pig ileal strips to LTD4."\\+"The methanolic extract of the roots of Asiasarum sieboldi has been evaluated for anti-allergic effects on various experimental models in vitro and in vivo. Bioassay-guided fractionation of the methanolic extract resulted in isolation of suppressive compounds in the PCA test: methyleugenol (1), elemicin (2), gamma-asarone (3), (-)-asarinin (4), and (-)-sesamin (5). Furthermore, elemicin (2) and (2E,4E,8Z,10E)-N-isobutyl-2,4,8,10-dodecatetraenamide (6) were found to exhibit an inhibitory action on 5-lipoxygenase (5-LOX) from RBL-1 cells. 3',4'-Dimethoxycinnamaldehyde (7) and xanthoxylol (8) potently reduced the contractile response of guinea pig ileal strips to LTD4."\\
 [Studies on anti-allergic components in the roots of Asiasarum sieboldi., Hashimoto, K., Yanagisawa, T., Okui, Y., Ikeya, Y., Maruno, M., Fujita, T., Planta medica, 60(2), 1994, 124-127]  [Studies on anti-allergic components in the roots of Asiasarum sieboldi., Hashimoto, K., Yanagisawa, T., Okui, Y., Ikeya, Y., Maruno, M., Fujita, T., Planta medica, 60(2), 1994, 124-127] 
  
asarum_sieboldii_miq.txt · Zuletzt geändert: 2015/12/22 07:41 von andreas