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asarum_heterotropoides_f._schmidt [2015/07/02 07:50]
andreas
asarum_heterotropoides_f._schmidt [2015/07/02 07:56] (aktuell)
andreas
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 Two lignanes, asarinin and xanthoxylol,​ were isolated and exhidited ​ antitumor effects in mice. \\ Two lignanes, asarinin and xanthoxylol,​ were isolated and exhidited ​ antitumor effects in mice. \\
 [Takasaki M, Konoshima T, Yasuda I, Hamano T, Tokuda H, Biol.Pharm.Bull.,​ 20(7), 1997, 776-780] [Takasaki M, Konoshima T, Yasuda I, Hamano T, Tokuda H, Biol.Pharm.Bull.,​ 20(7), 1997, 776-780]
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-The amounts of toxic aristolochic acids I and II in four groups of medicinal plants from the Aristolochiaceae and some related plants were determined by high-pressure liquid chromatography,​ but Asarum sieboldii (Usuba-saishin),​ Asarum heterotropoides (Keirin–saishin),​ Asarum sieboldii var. seoulense (Usuge-saishin) and commercial `Saishin'​ Asarum sect. Asiasarum sp. (Korean market) contained none. \\ 
-[Quantitative analysis of aristolochic acids, toxic compounds, contained in some medicinal plants., Hashimoto, K., Higuchi, M., Makino, B., Sakakibara, I., Kubo, M., Komatsu, Y., Okada, M., Journal of ethnopharmacology,​ 64(2), 1999, 185-189] ​ 
  
 Root extracts (80% EtOH, LC) of A. heterotropoides contained tetrahydrofuran lignans, aristolactams,​ an aristolochic acid derivative, three flavanones, two monoterpenes,​ and four phenolics. Among the 22 tested compounds, two (7-methoxyaristololactam IV, and (7α,​7'​β,​8α,​8'​α)-3,​4-methylenedioxy-3',​4'​-dihydroxy-7,​9':​7',​9-diepoxy-lignane) induced the downregulation of NO production, FOXP3 expression, and HIF-1α transcriptional activity. \\ Root extracts (80% EtOH, LC) of A. heterotropoides contained tetrahydrofuran lignans, aristolactams,​ an aristolochic acid derivative, three flavanones, two monoterpenes,​ and four phenolics. Among the 22 tested compounds, two (7-methoxyaristololactam IV, and (7α,​7'​β,​8α,​8'​α)-3,​4-methylenedioxy-3',​4'​-dihydroxy-7,​9':​7',​9-diepoxy-lignane) induced the downregulation of NO production, FOXP3 expression, and HIF-1α transcriptional activity. \\
asarum_heterotropoides_f._schmidt.txt · Zuletzt geändert: 2015/07/02 07:56 von andreas