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--- asarum_heterotropoides_f._schmidt [2015/06/30 17:21]
andreas
+++ asarum_heterotropoides_f._schmidt [2015/07/02 07:50]
andreas
@@ Zeile 13: / Zeile 13: @@
 Two lignanes, asarinin and xanthoxylol, were isolated and exhidited  antitumor effects in mice. \\
 [Takasaki M, Konoshima T, Yasuda I, Hamano T, Tokuda H, Biol.Pharm.Bull., 20(7), 1997, 776-780]
+The amounts of toxic aristolochic acids I and II in four groups of medicinal plants from the Aristolochiaceae and some related plants were determined by high-pressure liquid chromatography, but Asarum sieboldii (Usuba-saishin), Asarum heterotropoides (Keirin–saishin), Asarum sieboldii var. seoulense (Usuge-saishin) and commercial `Saishin' Asarum sect. Asiasarum sp. (Korean market) contained none. \\
+[Quantitative analysis of aristolochic acids, toxic compounds, contained in some medicinal plants., Hashimoto, K., Higuchi, M., Makino, B., Sakakibara, I., Kubo, M., Komatsu, Y., Okada, M., Journal of ethnopharmacology, 64(2), 1999, 185-189]
 Root extracts (80% EtOH, LC) of A. heterotropoides contained tetrahydrofuran lignans, aristolactams, an aristolochic acid derivative, three flavanones, two monoterpenes, and four phenolics. Among the 22 tested compounds, two (7-methoxyaristololactam IV, and (7α,7'β,8α,8'α)-3,4-methylenedioxy-3',4'-dihydroxy-7,9':7',9-diepoxy-lignane) induced the downregulation of NO production, FOXP3 expression, and HIF-1α transcriptional activity. \\
 [Bioactive Compounds from the Roots of Asiasarum heterotropoides., Lee, J., Lee, Y.J., Oh, S.M., Yi, J.M., Kim, N.S., Bang, O.S., Molecules, 19(1), 2013, 122-138] [[http://www.mdpi.com/1420-3049/19/1/122/htm]]
+"The main compounds in analyzed samples were methyl eugenol (22.58%), pentadecane (6.78%), 2,3,5-trimethoxytoluene (5.54%), 4-(chloromethyl) cyclohexene (3.36%), myristicine (3.27%), sesamin (3.24%), and kakoul (2-hydroxy-4,5-methylenedioxypropiophenone, 2.63%)... EOAH [essential oil from Asarum heterotropoides] at higher doses (1.0 and 2.0 g) reduced immobility time in the forced swimming test and tail suspension test. In addition, EOAH at a dose of 1.0 g significantly reduced the expected increases in the expression of corticotropin releasing factor positive neurons in the paraventricular nucleus and the expression of tyrosine hydroxylase positive neurons in the locus coeruleus, and the expected decreases of the 5-HT positive neurons in the dorsal raphe nucleus." \\
+[Effect of the fragrance inhalation of essential oil from Asarum heterotropoides on depression-like behaviors in mice., Park, H.J., Lim, E.J., Zhao, R.J., Oh, S.R., Jung, J.W., Ahn, E.M., Yang, C.H., BMC complementary and alternative medicine, 15(1), 2015, 43] [[http://www.biomedcentral.com/1472-6882/15/43]]
+pictures: [[http://www.asianflora.com/Aristolochiaceae/Asarum-heterotropoides.htm]]

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