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asarum_europaeum_l [2016/07/10 16:39]
andreas
asarum_europaeum_l [2017/01/02 17:57]
andreas
Zeile 7: Zeile 7:
 [The Active Substances of Asarum europaeum., Gracza, L., Planta medica, 48(7), 1983, 153-157] [The Active Substances of Asarum europaeum., Gracza, L., Planta medica, 48(7), 1983, 153-157]
  
-{{:isoeugen_asa.jpg|}} (E)-asarone (R=OCH3, α-asarone) \\ (E)-methyl isoeugenol (isoeugenol methyl ether, R=H)+|{{:isoeugen_asa.jpg|}} \\ (E)-asarone (R=OCH3, α-asarone) \\ (E)-methyl isoeugenol (isoeugenol methyl ether, R=H)|
  
 "The locally strong irritant effect and the pepper-like burning taste of the drug is ascribed to trans-isoasarone... Extracts of the drug cause vomit, laxative and diuretic. In former times, the rhizome was used as emetic and sneezing powder. The root was used in folk medicine to treat diseases of the kidney, bladder, liver, and inflammation of the upper respiratory tract. Further application of the decoction is not encouraged, as side effects can not be excluded." \\ "The locally strong irritant effect and the pepper-like burning taste of the drug is ascribed to trans-isoasarone... Extracts of the drug cause vomit, laxative and diuretic. In former times, the rhizome was used as emetic and sneezing powder. The root was used in folk medicine to treat diseases of the kidney, bladder, liver, and inflammation of the upper respiratory tract. Further application of the decoction is not encouraged, as side effects can not be excluded." \\
Zeile 21: Zeile 21:
 [Hagers Handbuch der Pharmazeutischen Praxis, Springer 2010]   [Hagers Handbuch der Pharmazeutischen Praxis, Springer 2010]  
  
-In 2010, the use of all plants belonging to the Asarum species in drugs was banned in Germany by decree of the Federal Institute for Drugs and Medical Devices (BfArM). The cause of this was the detection of aristolochic acid I in homeopathic mother tinctures of Asarum europaeum with approximately 0.044 - 0.13 ppm, and of Asarum canadense with approximately 127.4g/kg (about 0.13 ppm). \\+In 2010, the use of all plants belonging to the Asarum species in drugs was banned in Germany by decree of the Federal Institute for Drugs and Medical Devices (BfArM). The cause of this was the detection of aristolochic acid I in homeopathic mother tinctures of Asarum europaeum with 3.8-85.0 μg/kg (0.044-0.085 ppm), and of Asarum canadense with approximately 127.4µg/kg (about 0.13 ppm). \\
 [[http://www.bfarm.de/SharedDocs/Downloads/DE/Arzneimittel/Pharmakovigilanz/Risikoinformationen/RisikoBewVerf/a-f/aristolochia_bescheid.pdf?__blob=publicationFile&v=2]] [[http://www.bfarm.de/SharedDocs/Downloads/DE/Arzneimittel/Pharmakovigilanz/Risikoinformationen/RisikoBewVerf/a-f/aristolochia_bescheid.pdf?__blob=publicationFile&v=2]]
  
asarum_europaeum_l.txt · Zuletzt geändert: 2017/01/02 17:57 von andreas