Tinkturenpresse

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Angelica sinensis

„Bioassay-guided fractionation of the chloroform extract from the roots of Angelica sinensis led to isolation and characterization of (Z)-ligustilide using direct-bioautography with Colletotrichum species. The structure of (Z)-ligustilide was confirmed by 1H and 13C NMR spectroscopy and GC/MS. (Z)-Ligustilide deterred the biting of two mosquito species more effectively than DEET. Three different A. sinensis accessions and one Angelica archangelica root oil were evauated by GC and GC/MS, and the dominant component in A. sinensis was 61−69% (Z)-ligustilide. Two other prominent compounds in A. sinensis oils were 5.7−9.8% (E)-3-butylidene phthalide and 1.5−2.3% (Z)-3-butylidene phthalide….
(Z)-Ligustilide is unstable in air and requires refrigeration and is best stored under nitrogen at 4°C in an amber vial.“ [Bioactivity-guided fractionation and GC/MS fingerprinting of Angelica sinensis and Angelica archangelica root components for antifungal and mosquito deterrent activity. Wedge, D. E., Klun, J. A., Tabanca, N., Demirci, B., Ozek, T., Baser, K. H. C., Zhang, J. (2008)., Journal of agricultural and food chemistry, 57(2), 2009, 464-470] http://www.afpmb.org/sites/default/files/pubs/dwfp/publications/FY09/Wedge/Wedge2009.pdf