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anemarrhena_asphodeloides_bunge [2015/03/29 11:01] andreas angelegt |
anemarrhena_asphodeloides_bunge [2015/06/13 11:37] (aktuell) |
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hana suge (jap.), 知母 zhi mu (chin.) | hana suge (jap.), 知母 zhi mu (chin.) | ||
- | Perennial | + | Erect perennial |
+ | [[http:// | ||
The rhizomes are used as antipyretic, | The rhizomes are used as antipyretic, | ||
[[http:// | [[http:// | ||
- | The plant contains the steroidal saponins anemarrhenasaponin I, anemarrhenasaponin Ia, timosaponin BI, timosaponin BII, timosaponin B, timosaponin AIII, and timosaponin F. \\ | + | The plant contains the coprostane type steroidal saponins anemarrhenasaponin I-IV, timosaponin BI, timosaponin BII, timosaponin AIII, and timosaponin F as well as and a xanthone C-glycoside, |
- | [Steroidal saponins from Anemarrhena asphodeloides and their effects on superoxide generation., | + | [New steroidal saponins from the rhizomes of Anemarrhena asphodeloides Bunge (Liliaceae)., |
+ | [Steroidal saponins from Anemarrhena asphodeloides and their effects on superoxide generation., | ||
"The antidiabetic activity of the rhizoma of Anemarrhena asphodeloides was investigated in KK-Ay mice, an animal model of genetic type 2 diabetes. The water extract of the rhizoma (AA) (90 mg/kg) reduced blood glucose levels from 570±29 to 401±59 mg/dl 7 h after oral administration (p<0.05) and also tended to reduce serum insulin levels in KK-Ay mice. AA-treated KK-Ay mice had significantly reduced blood glucose levels in an insulin tolerance test. Based on these results, the antidiabetic mechanism of AA may be due to decreased insulin resistance. In addition, the active components of AA were confirmed to be mangiferin and its glucoside." | "The antidiabetic activity of the rhizoma of Anemarrhena asphodeloides was investigated in KK-Ay mice, an animal model of genetic type 2 diabetes. The water extract of the rhizoma (AA) (90 mg/kg) reduced blood glucose levels from 570±29 to 401±59 mg/dl 7 h after oral administration (p<0.05) and also tended to reduce serum insulin levels in KK-Ay mice. AA-treated KK-Ay mice had significantly reduced blood glucose levels in an insulin tolerance test. Based on these results, the antidiabetic mechanism of AA may be due to decreased insulin resistance. In addition, the active components of AA were confirmed to be mangiferin and its glucoside." | ||
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[Growth inhibition and apoptosis of gastric cancer cell lines by Anemarrhena asphodeloides Bunge., Takeda, Y., Togashi, H., Matsuo, T., Shinzawa, H., Takeda, Y., Takahashi, T., Journal of gastroenterology, | [Growth inhibition and apoptosis of gastric cancer cell lines by Anemarrhena asphodeloides Bunge., Takeda, Y., Togashi, H., Matsuo, T., Shinzawa, H., Takeda, Y., Takahashi, T., Journal of gastroenterology, | ||
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+ | [Insulin secretion is stimulated by ethanol extract of Anemarrhena asphodeloides in isolated islet of healthy Wistar and diabetic Goto-Kakizaki Rats., Hoa, N.K., Phan, D.V., Thuan, N.D., Ostenson, C.G., Experimental and Clinical Endocrinology and Diabetes, Vol.112(9), 2004, 520-525] | ||
Anemarsaponin B from the rhizomes of A.asphodeloides was found to have an anti-inflammatory effect, possibly via the p38 MAP kinase pathway. \\ | Anemarsaponin B from the rhizomes of A.asphodeloides was found to have an anti-inflammatory effect, possibly via the p38 MAP kinase pathway. \\ | ||
[Anti-inflammatory effect of anemarsaponin B isolated from the rhizomes of Anemarrhena asphodeloides in LPS-induced RAW 264.7 macrophages is mediated by negative regulation of the nuclear factor-κB and p38 pathways., Kim, J.Y., Shin, J.S., Ryu, J.H., Kim, S.Y., Cho, Y.W., Choi, J.H., Lee, K.T., Food and chemical toxicology, Vol.47(7), 2009, 1610-1617] | [Anti-inflammatory effect of anemarsaponin B isolated from the rhizomes of Anemarrhena asphodeloides in LPS-induced RAW 264.7 macrophages is mediated by negative regulation of the nuclear factor-κB and p38 pathways., Kim, J.Y., Shin, J.S., Ryu, J.H., Kim, S.Y., Cho, Y.W., Choi, J.H., Lee, K.T., Food and chemical toxicology, Vol.47(7), 2009, 1610-1617] | ||
+ | Used in TCM as decoction to treat feaver as symptom of infectious diseases like pneumonia, tuberculosis, | ||
+ | [Hagers Handbuch der Pharmazeutischen Praxis, Springer 2010] | ||
- | ? JP XII, Hager, ChinP IX |