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alchornea_cordifolia_muell._arg

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alchornea_cordifolia_muell._arg [2015/11/13 18:09]
andreas angelegt
alchornea_cordifolia_muell._arg [2015/11/13 18:18] (aktuell)
andreas
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 Evergreen shrub or tree, up to 10m high, native to the tropical Africa; leaves alternate, ovate-elliptic, cordate, longer petioled; male axillary inflorescences 30cm long, with small pale green flowers; female flowers with 2-3 dark red styles; fruit a hairy, green to red colored capsule with scarlet ovoid seeds. Evergreen shrub or tree, up to 10m high, native to the tropical Africa; leaves alternate, ovate-elliptic, cordate, longer petioled; male axillary inflorescences 30cm long, with small pale green flowers; female flowers with 2-3 dark red styles; fruit a hairy, green to red colored capsule with scarlet ovoid seeds.
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 +The 50% aqueous ethanol extract of A. cordifolia showed antimicrobial ativity especially against  gram-positive  bacteria and some yeasts with inhibitory concentrations under 5 mg/mL. \\
 +[Antimicrobial spectrum of Alchornea cordifolia leaf extract., Okeke, I.N., Ogundaini, A.O., Ogungbamila, F.O., Lamikanra, A., Phytotherapy Research, 13(1), 1999, 67-69]
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 +Some fractions of a methanolic A.cordifolia leaf extract, notably those containing phenolics and terpenoids, exhibited significant antimicrobial activity against Pseudomonas aeruginosa, Bacillus subtilis and Escherichia coli. \\
 +[Antimicrobial activities of Alchornea cordifolia., Ebi, G.C., Fitoterapia, 72(1), 2001, 69-72]
  
 "Alchornea cordifolia is one of the most widely-used plants in traditional medicine throughout Africa, principally for inflammatory, antimicrobial and parasitic diseases. In continuation of our investigations on its anti-inflammatory activity, we fractionated the leaf and root bark extracts and isolated six compounds which exhibited significant topical anti-inflammatory activity in the mouse ear oedema model using croton oil at a dose of 90 μg/cm2. Daucosterol (2), acetyl aleuritolic acid (4), N1,N2-diisopentenyl guanidine (5) and N1,N2,N3-triisopentenyl guanidine (6) were shown to be more active than indomethacin, while β-sitosterol (1) and di(2-ethylhexyl) phthalate (3) were less effective. This is the first report on the presence of compounds 1, 2, 3 and 4 in this plant and of the anti-inflammatory activity of 3, 5 and 6. These compounds may account, at least in part, for the use of A. cordifolia in folk medicine to treat inflammation." \\ "Alchornea cordifolia is one of the most widely-used plants in traditional medicine throughout Africa, principally for inflammatory, antimicrobial and parasitic diseases. In continuation of our investigations on its anti-inflammatory activity, we fractionated the leaf and root bark extracts and isolated six compounds which exhibited significant topical anti-inflammatory activity in the mouse ear oedema model using croton oil at a dose of 90 μg/cm2. Daucosterol (2), acetyl aleuritolic acid (4), N1,N2-diisopentenyl guanidine (5) and N1,N2,N3-triisopentenyl guanidine (6) were shown to be more active than indomethacin, while β-sitosterol (1) and di(2-ethylhexyl) phthalate (3) were less effective. This is the first report on the presence of compounds 1, 2, 3 and 4 in this plant and of the anti-inflammatory activity of 3, 5 and 6. These compounds may account, at least in part, for the use of A. cordifolia in folk medicine to treat inflammation." \\
alchornea_cordifolia_muell._arg.txt · Zuletzt geändert: 2015/11/13 18:18 von andreas