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alchornea_cordifolia_muell._arg

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alchornea_cordifolia_muell._arg [2015/11/13 18:09]
andreas angelegt
alchornea_cordifolia_muell._arg [2015/11/13 18:18] (aktuell)
andreas
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 Evergreen shrub or tree, up to 10m high, native to the tropical Africa; leaves alternate, ovate-elliptic,​ cordate, longer petioled; male axillary inflorescences 30cm long, with small pale green flowers; female flowers with 2-3 dark red styles; fruit a hairy, green to red colored capsule with scarlet ovoid seeds. Evergreen shrub or tree, up to 10m high, native to the tropical Africa; leaves alternate, ovate-elliptic,​ cordate, longer petioled; male axillary inflorescences 30cm long, with small pale green flowers; female flowers with 2-3 dark red styles; fruit a hairy, green to red colored capsule with scarlet ovoid seeds.
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 +The 50% aqueous ethanol extract of A. cordifolia showed antimicrobial ativity especially against ​ gram-positive ​ bacteria and some yeasts with inhibitory concentrations under 5 mg/mL. \\
 +[Antimicrobial spectrum of Alchornea cordifolia leaf extract., Okeke, I.N., Ogundaini, A.O., Ogungbamila,​ F.O., Lamikanra, A., Phytotherapy Research, 13(1), 1999, 67-69]
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 +Some fractions of a methanolic A.cordifolia leaf extract, notably those containing phenolics and terpenoids, exhibited significant antimicrobial activity against Pseudomonas aeruginosa, Bacillus subtilis and Escherichia coli. \\
 +[Antimicrobial activities of Alchornea cordifolia.,​ Ebi, G.C., Fitoterapia,​ 72(1), 2001, 69-72]
  
 "​Alchornea cordifolia is one of the most widely-used plants in traditional medicine throughout Africa, principally for inflammatory,​ antimicrobial and parasitic diseases. In continuation of our investigations on its anti-inflammatory activity, we fractionated the leaf and root bark extracts and isolated six compounds which exhibited significant topical anti-inflammatory activity in the mouse ear oedema model using croton oil at a dose of 90 μg/cm2. Daucosterol (2), acetyl aleuritolic acid (4), N1,​N2-diisopentenyl guanidine (5) and N1,​N2,​N3-triisopentenyl guanidine (6) were shown to be more active than indomethacin,​ while β-sitosterol (1) and di(2-ethylhexyl) phthalate (3) were less effective. This is the first report on the presence of compounds 1, 2, 3 and 4 in this plant and of the anti-inflammatory activity of 3, 5 and 6. These compounds may account, at least in part, for the use of A. cordifolia in folk medicine to treat inflammation."​ \\ "​Alchornea cordifolia is one of the most widely-used plants in traditional medicine throughout Africa, principally for inflammatory,​ antimicrobial and parasitic diseases. In continuation of our investigations on its anti-inflammatory activity, we fractionated the leaf and root bark extracts and isolated six compounds which exhibited significant topical anti-inflammatory activity in the mouse ear oedema model using croton oil at a dose of 90 μg/cm2. Daucosterol (2), acetyl aleuritolic acid (4), N1,​N2-diisopentenyl guanidine (5) and N1,​N2,​N3-triisopentenyl guanidine (6) were shown to be more active than indomethacin,​ while β-sitosterol (1) and di(2-ethylhexyl) phthalate (3) were less effective. This is the first report on the presence of compounds 1, 2, 3 and 4 in this plant and of the anti-inflammatory activity of 3, 5 and 6. These compounds may account, at least in part, for the use of A. cordifolia in folk medicine to treat inflammation."​ \\
alchornea_cordifolia_muell._arg.txt · Zuletzt geändert: 2015/11/13 18:18 von andreas