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--- ageratum_conyzoides_l [2015/03/14 13:00]
andreas
+++ ageratum_conyzoides_l [2015/06/13 11:36] (aktuell)
@@ Zeile 33: / Zeile 33: @@
 [Ageratum conyzoides essential oil as aflatoxin suppressor of Aspergillus flavus., Nogueira, J.H., Gonçalez, E., Galleti, S.R., Facanali, R., Marques, M.O., Felício, J.D., International journal of food microbiology, Vol.137(1), 2010, 55-60]
-"Aqueous extracts of Ageratum conyzoides L. harvested in Brazil (commercial, flowering and non-flowering samples) were prepared according to the prescribed method and analyzed by HPLC-HRMS. The pyrrolizidine alkaloids lycopsamine, dihydrolycopsamine, and acetyl-lycopsamine and their N-oxides, were detected in the analyzed extracts, lycopsamine and its N-oxide being known hepatotoxins and tumorigens." \\
+"Aqueous extracts of Ageratum conyzoides L. harvested in Brazil (commercial, flowering and non-flowering samples) were prepared according to the prescribed method and analyzed by HPLC-HRMS. The pyrrolizidine alkaloids lycopsamine, dihydrolycopsamine, and acetyl-lycopsamine and their N-oxides, were detected in the analyzed extracts, lycopsamine and its N-oxide being known hepatotoxins and tumorigens. Together with the pyrrolizidine alkaloids identified by HPLC-HRMS, thirteen phenolic compounds were identified, notably, methoxylated flavonoids and chromenes. Toxicological studies on A. conyzoides are necessary, as is monitoring of its clinical use. To date, there are no established safety guidelines on pyrrolizidine alkaloids-containing plants, and their use in Brazil." \\
 [Pyrrolizidine alkaloids in medicinal tea of Ageratum conyzoides, Bosi C.F. et al., Revista Brasileira de Farmacognosia, Vol.23(3), 2013, 425–432]

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