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tussilago_farfara_l [2015/04/15 12:25] andreastussilago_farfara_l [2017/03/29 09:00] (aktuell) andreas
Zeile 8: Zeile 8:
 Dried leaves of coltsfoot (Farfarae folium) is used to treat dry cough and as an expectorant. Mucus-forming substances of the hot water extract from the leaves cover mucous membranes of the throat and thus reduce the urge to cough. \\ Dried leaves of coltsfoot (Farfarae folium) is used to treat dry cough and as an expectorant. Mucus-forming substances of the hot water extract from the leaves cover mucous membranes of the throat and thus reduce the urge to cough. \\
 [Wichtl, Max. Teedrogen, Teedrogen und Phytopharmaka, Stuttgart 2002]  [Wichtl, Max. Teedrogen, Teedrogen und Phytopharmaka, Stuttgart 2002] 
 +
 +Flos Farfara (dried flower buds of T.farfara, 'Kuandonghua'), are an important traditional Chinese medicine,
 +widely used for the treatment of cough, bronchitis and asthmatic disorders. \\
 +[Committee for the Pharmacopoeia of People’s Republic of China, 2010]
  
 "Chemical studies on the dried, young flowers used in this experiment suggested that the carcinogenicity of coltsfoot is most probably due to senkirkine, a hepatotoxic pyrrolizidine alkaloid." \\ "Chemical studies on the dried, young flowers used in this experiment suggested that the carcinogenicity of coltsfoot is most probably due to senkirkine, a hepatotoxic pyrrolizidine alkaloid." \\
Zeile 21: Zeile 25:
  
 "Tussilagone (TSL), isolated from the flower of buds of Tussilago farfara (Compositae), is a sesquiterpenoid that is known to exert a variety of pharmacological activities. In the present study, we demonstrated that TSL exerts anti-inflammatory activities in murine macrophages by inducing heme oxygenase-1 (HO-1) expression." \\ "Tussilagone (TSL), isolated from the flower of buds of Tussilago farfara (Compositae), is a sesquiterpenoid that is known to exert a variety of pharmacological activities. In the present study, we demonstrated that TSL exerts anti-inflammatory activities in murine macrophages by inducing heme oxygenase-1 (HO-1) expression." \\
-[The anti-inflammatory effect of tussilagone, from< i> Tussilago farfara</i>, is mediated by the induction of heme oxygenase-1 in murine macrophages. Hwangbo, C., Lee, H. S., Park, J., Choe, J., & Lee, J. H. International immunopharmacology, Vol.9(13), 2009, 1578-1584]+[The anti-inflammatory effect of tussilagone, from //Tussilago farfara//, is mediated by the induction of heme oxygenase-1 in murine macrophages. Hwangbo, C., Lee, H. S., Park, J., Choe, J., & Lee, J. H. International immunopharmacology, Vol.9(13), 2009, 1578-1584] \\ 
 +[[http://cc.kangwon.ac.kr/~immunology/CIB_informations/Journal_choe/choe39.pdf]] 
 + 
 +{{:tussilagone.jpg|}} tussilagone 
 + 
 +"Preparative high-speed counter-current chromatography (HSCCC) was successfully applied for separation and purification of sesquiterpenoids from an extract of Tussilago farfara... The separation produced a total of 32 mg of tussilagone, 18 mg of 14-acetoxy-7β-(3'-ethyl cis-crotonoyloxy)-1α-(2'-methyl butyryloxy)-notonipetranone and 21 mg of 7β-(3'-ethyl cis-crotonoyloxy)-1α-(2'-methyl butyryloxy)-3,14-dehydro-Z-notonipetranone from 500 mg of the crude extract in one step separation..." \\ 
 +[Preparative separation and purification of sesquiterpenoids from Tussilago farfara L. by high-speed counter-current chromatography., Wang, D., Fang, L., Wang, X., Qiu, J., Huang, L., Química Nova, Vol.34(5), 2011, 804-807] \\ 
 +[[http://www.scielo.br/scielo.php?pid=S0100-40422011000500014&script=sci_arttext]]
  
-{{http://upload.wikimedia.org/wikipedia/commons/thumb/8/84/Illustration_Tussilago_farfara0.jpg/640px-Illustration_Tussilago_farfara0.jpg?500}}+{{:tussilago.jpg?500}} \\ 
 +Thomé, O.W., Flora von Deutschland Österreich und der Schweiz, Tafeln, vol.4, t.565 (1885) \\ 
 +[[http://plantgenera.org/species.php?id_species=1040436]]
tussilago_farfara_l.1429100745.txt.gz · Zuletzt geändert: 2015/04/15 12:25 von andreas

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