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tussilago_farfara_l [2015/04/15 12:25] – andreas | tussilago_farfara_l [2017/03/29 09:00] (aktuell) – andreas |
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Dried leaves of coltsfoot (Farfarae folium) is used to treat dry cough and as an expectorant. Mucus-forming substances of the hot water extract from the leaves cover mucous membranes of the throat and thus reduce the urge to cough. \\ | Dried leaves of coltsfoot (Farfarae folium) is used to treat dry cough and as an expectorant. Mucus-forming substances of the hot water extract from the leaves cover mucous membranes of the throat and thus reduce the urge to cough. \\ |
[Wichtl, Max. Teedrogen, Teedrogen und Phytopharmaka, Stuttgart 2002] | [Wichtl, Max. Teedrogen, Teedrogen und Phytopharmaka, Stuttgart 2002] |
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| Flos Farfara (dried flower buds of T.farfara, 'Kuandonghua'), are an important traditional Chinese medicine, |
| widely used for the treatment of cough, bronchitis and asthmatic disorders. \\ |
| [Committee for the Pharmacopoeia of People’s Republic of China, 2010] |
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"Chemical studies on the dried, young flowers used in this experiment suggested that the carcinogenicity of coltsfoot is most probably due to senkirkine, a hepatotoxic pyrrolizidine alkaloid." \\ | "Chemical studies on the dried, young flowers used in this experiment suggested that the carcinogenicity of coltsfoot is most probably due to senkirkine, a hepatotoxic pyrrolizidine alkaloid." \\ |
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"Tussilagone (TSL), isolated from the flower of buds of Tussilago farfara (Compositae), is a sesquiterpenoid that is known to exert a variety of pharmacological activities. In the present study, we demonstrated that TSL exerts anti-inflammatory activities in murine macrophages by inducing heme oxygenase-1 (HO-1) expression." \\ | "Tussilagone (TSL), isolated from the flower of buds of Tussilago farfara (Compositae), is a sesquiterpenoid that is known to exert a variety of pharmacological activities. In the present study, we demonstrated that TSL exerts anti-inflammatory activities in murine macrophages by inducing heme oxygenase-1 (HO-1) expression." \\ |
[The anti-inflammatory effect of tussilagone, from< i> Tussilago farfara</i>, is mediated by the induction of heme oxygenase-1 in murine macrophages. Hwangbo, C., Lee, H. S., Park, J., Choe, J., & Lee, J. H. International immunopharmacology, Vol.9(13), 2009, 1578-1584] | [The anti-inflammatory effect of tussilagone, from //Tussilago farfara//, is mediated by the induction of heme oxygenase-1 in murine macrophages. Hwangbo, C., Lee, H. S., Park, J., Choe, J., & Lee, J. H. International immunopharmacology, Vol.9(13), 2009, 1578-1584] \\ |
| [[http://cc.kangwon.ac.kr/~immunology/CIB_informations/Journal_choe/choe39.pdf]] |
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| {{:tussilagone.jpg|}} tussilagone |
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| "Preparative high-speed counter-current chromatography (HSCCC) was successfully applied for separation and purification of sesquiterpenoids from an extract of Tussilago farfara... The separation produced a total of 32 mg of tussilagone, 18 mg of 14-acetoxy-7β-(3'-ethyl cis-crotonoyloxy)-1α-(2'-methyl butyryloxy)-notonipetranone and 21 mg of 7β-(3'-ethyl cis-crotonoyloxy)-1α-(2'-methyl butyryloxy)-3,14-dehydro-Z-notonipetranone from 500 mg of the crude extract in one step separation..." \\ |
| [Preparative separation and purification of sesquiterpenoids from Tussilago farfara L. by high-speed counter-current chromatography., Wang, D., Fang, L., Wang, X., Qiu, J., Huang, L., Química Nova, Vol.34(5), 2011, 804-807] \\ |
| [[http://www.scielo.br/scielo.php?pid=S0100-40422011000500014&script=sci_arttext]] |
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{{http://upload.wikimedia.org/wikipedia/commons/thumb/8/84/Illustration_Tussilago_farfara0.jpg/640px-Illustration_Tussilago_farfara0.jpg?500}} | {{:tussilago.jpg?500}} \\ |
| Thomé, O.W., Flora von Deutschland Österreich und der Schweiz, Tafeln, vol.4, t.565 (1885) \\ |
| [[http://plantgenera.org/species.php?id_species=1040436]] |