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saposhnikovia_divaricata_turcz._schischk

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saposhnikovia_divaricata_turcz._schischk [2014/09/02 22:41] – angelegt andreassaposhnikovia_divaricata_turcz._schischk [2015/12/28 17:21] (aktuell) andreas
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 Saposhnikovia divaricata (Turcz.) Schischk. - syn. Ledebouriella divaricata (Turczaninow) M. Hiroe; Apiaceae \\ Saposhnikovia divaricata (Turcz.) Schischk. - syn. Ledebouriella divaricata (Turczaninow) M. Hiroe; Apiaceae \\
-laserwort, fang feng 防風 (chin.), +fang feng 防風 (chin.), **Saposhnikovia**
  
-native to East Asia (Siberia, Korea, China);+Plant up to 80cm tall, native to North East Asia (Siberia, Korea, China); rootstock to 2cm thick; leaves 2-pinnate; pinnae 3-4 pairs, leaflets oblong-ovate to broad-ovate, ultimate segments linear-lanceolate or cuneate-obovate; umbels numerous, ca. 6cm across, umbellules 4-5-flowered, petals ca. 1.5mm; fruits 4-5 × 2-3 mm. The root is used as the important traditional Chinese medicine “fang feng.” [[http://www.efloras.org/florataxon.aspx?flora_id=2&taxon_id=200015899]]
  
 The dried roots of S. divaricata are used for the treatment of rheumatism, headache, convulsion and nerve The dried roots of S. divaricata are used for the treatment of rheumatism, headache, convulsion and nerve
-paralysis in tradinional chinese and korean medicine. \\+paralysis in traditional medicine of China and Korea. \\
 [Bae, K. H., The Medicinal Plants of Korea; Kyo-Hak: Seoul, 2000; 380] [Bae, K. H., The Medicinal Plants of Korea; Kyo-Hak: Seoul, 2000; 380]
  
-Panaxynol was found to be the main constituent of the essential oil from the root of S.divaricata. \\+[[http://www.chemblink.com/products/21852-80-2.htm|Panaxynol (falcarinol)]] was found to be the main constituent of the essential oil from the root of S.divaricata. \\
 [GC-MS Analysis of the essential oil from the root of //Saposhnikovia divaricat//a (Turcz.) Schischk., Li, Ji, Xu Zhiling, and Pan Jiongguang., Natural Product Research and Development 4, 1995, 1] [GC-MS Analysis of the essential oil from the root of //Saposhnikovia divaricat//a (Turcz.) Schischk., Li, Ji, Xu Zhiling, and Pan Jiongguang., Natural Product Research and Development 4, 1995, 1]
  
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 [Chemical constituents of Saposhnikovia divaricata. Kim, S. J., et al., Korean Journal of Pharmacognosy,2008] [Chemical constituents of Saposhnikovia divaricata. Kim, S. J., et al., Korean Journal of Pharmacognosy,2008]
  
-"Anomalin, a pyranocoumarin constituent of S. divaricata, exhibits potent anti-inflammatory activity... several pro-inflammatory cytokines, including tumor necrosis factor-α (TNF-α) and interleukin-6 (IL-6), were reduced by anomalin, and this reduction correlated with the down-regulation of the NF-κB signaling pathway. In addition, anomalin suppressed the LPS-induced phosphorylation and degradation of IκBα... LPS-induced NF-κB DNA binding was drastically abolished by anomalin. The present data suggest that anomalin is a major anti-inflammatory agent and may be a potential therapeutic candidate for the treatment of inflammatory disorders." \\+"[[http://www.chemblink.com/products/81740-07-0.htm|Anomalin]], a pyranocoumarin constituent of S. divaricata, exhibits potent anti-inflammatory activity... several pro-inflammatory cytokines, including tumor necrosis factor-α (TNF-α) and interleukin-6 (IL-6), were reduced by anomalin, and this reduction correlated with the down-regulation of the NF-κB signaling pathway. In addition, anomalin suppressed the LPS-induced phosphorylation and degradation of IκBα... LPS-induced NF-κB DNA binding was drastically abolished by anomalin. The present data suggest that anomalin is a major anti-inflammatory agent and may be a potential therapeutic candidate for the treatment of inflammatory disorders." \\
 [Suppression of LPS‐induced inflammatory and NF‐κB responses by anomalin in RAW 264.7 macrophages. Khan, Salman, et al., Journal of cellular biochemistry, Vol.112(8), 2011, 2179-2188] [Suppression of LPS‐induced inflammatory and NF‐κB responses by anomalin in RAW 264.7 macrophages. Khan, Salman, et al., Journal of cellular biochemistry, Vol.112(8), 2011, 2179-2188]
  
 +{{:shapashnikovia_divaricata.jpg?700}} \\ 
 +S.divaricata as Trinia seseloides (Hoffm.) Ledeb.; Ledebour, C.F. von, Icones plantarum novarum, vol.1 t.8 (1829) \\ 
 +[[http://plantgenera.org/species.php?id_species=906045]]
saposhnikovia_divaricata_turcz._schischk.1409697674.txt.gz · Zuletzt geändert: 2014/09/02 22:41 von andreas

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