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--- peucedanum_ostruthium_l._koch [2015/02/26 15:42] – andreas
+++ peucedanum_ostruthium_l._koch [2015/06/13 09:39] (aktuell) – Externe Bearbeitung 127.0.0.1
@@ Zeile 21: / Zeile 21: @@
 [[http://zfn.mpdl.mpg.de/data/Reihe_C/56/ZNC-2001-56c-0930.pdf]]
-HPLC profiling of the CH2Cl2 extract led to the identification of seven coumarins as major constituents. "The total coumarin content in this CH2Cl2 extract was determined to be 78%, whereas the content per gram dry weight of plant material was 6%. Ostruthin was quantified as the main coumarin (41% of the total coumarin content), followed by oxypeucedanin (18%), ostruthol (13%), imperatorin (12%), isoimperatorin (9%), oxypeucedanin hydrate (6%), and osthole (1%)." \\
+HPLC profiling of the CH2Cl2 extract led to the identification of seven coumarins as major constituents. "The total coumarin content in this CH2Cl2 extract was determined to be 78%, whereas the content per gram dry weight of plant material was 6%. [[http://pubchem.ncbi.nlm.nih.gov/substance/11472#section=Top|Ostruthin]] was quantified as the main coumarin (41% of the total coumarin content), followed by oxypeucedanin (18%), ostruthol (13%), imperatorin (12%), isoimperatorin (9%), oxypeucedanin hydrate (6%), and osthole (1%)." \\
 [Identification of Ostruthin from Peucedanum ostruthium Rhizomes as an inhibitor of vascular smooth muscle cell proliferation., Joa, H., Vogl, S., Atanasov, A. G., Zehl, M., Nakel, T., Fakhrudin, N., Dirsch, V. M., Journal of natural products, Vol.74(6), 2011, 1513-1516] \\
 [[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3122331/]]
+{{:osthrutin.jpg|}} osthrutin
+Main coumarins of dichloromethane extracts of commercial P.ostruthium root samples were the linear furanocoumarins oxypeucedanin hydrate (2-7%), oxypeucedanin (17-20%), ostruthol (12-14%), imperatorin (12-15%), isoimperatorin (9-10%), and oxypeucedanin ethanolate and the simple coumarins osthole (1%) and ostruthin (38-41%). A chromone, peucenin, was identified by LC-MS only. \\
+[Identification and quantification of coumarins in Peucedanum ostruthium (L.) Koch by HPLC-DAD and HPLC-DAD-MS., Vogl, S., Zehl, M., Picker, P., Urban, E., Wawrosch, C., Reznicek, G., Kopp, B., Journal of agricultural and food chemistry, Vol.59(9), 2011, 4371-4377]
 {{http://plantgenera.org/ILLUSTRATIONS_HD/152292.jpg?500}} \\