Unterschiede

Hier werden die Unterschiede zwischen zwei Versionen angezeigt.

--- origanum_vulgare_l [2020/08/16 07:58] – andreas
+++ origanum_vulgare_l [2021/12/23 14:20] (aktuell) – andreas
@@ Zeile 29: / Zeile 29: @@
 "The major components of oregano essential oil were carvacrol, β-fenchyl alcohol, thymol, and γ-terpinene. Hot water extract had the strongest antioxidant properties and the highest phenolic content." \\
 [Chemical composition and bioactivity of different oregano (Origanum vulgare) extracts and essential oil. Teixeira, B., Marques, A., Ramos, C., Serrano, C., Matos, O., Neng, N. R., Nogueira, J. M. F., Saraiva, J. A. and Nunes, M. L. (2013),  J. Sci. Food Agric., 93: 2707–2714]
+"In thymol, carvacrol, p-cymene and thymohydroquinone biosynthesis, geranyl diphosphate (GDP) is first cyclized to γ-terpinene by the terpene synthase (TvTPS2). P450s hydroxylate γ-terpinene either at C-3 or C-6, and the dienol intermediates are converted by a short-chain dehydrogenase (SDR) to the corresponding ketones. These allylic ketones undergo keto-enol tautomerisms to form thymol and carvacrol. The formation of p-cymene results from the spontaneous rearrangement of the dienol intermediates due to their instability in aqueous conditions. Thymol and carvacrol are converted to thymohydroquinone by CYP76S40 or CYP736A300 and, subsequently, to thymoquinone by spontaneous conversion or enzymatic action." \\
+["The biosynthesis of thymol, carvacrol, and thymohydroquinone in Lamiaceae proceeds via cytochrome P450s and a short-chain dehydrogenase", Sandra T. Krause, Pan Liao, Christoph Crocoll, Benoît Boachon, Christiane Förster, Franziska Leidecker, Natalie Wiese, Dongyan Zhao, Joshua C. Wood, C. Robin Buell, Jonathan Gershenzon, Natalia Dudareva, Jörg Degenhardt; Proceedings of the National Academy of Sciences Dec 2021, 118 (52) e2110092118; DOI: 10.1073/pnas.2110092118] [[https://www.pnas.org/content/118/52/e2110092118]]
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