mitragyna_speciosa_korth
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| mitragyna_speciosa_korth [2015/08/02 08:59] – andreas | mitragyna_speciosa_korth [2018/02/08 05:42] (aktuell) – andreas | ||
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| involves ingestion of the plant’s raw leaves or consumption of teas that are brewed or steeped from the leaves. Kratom leaves are used for their complex, dose-dependent pharmacologic effects. Low to moderate doses (1-5 g) of the leaves reportedly produce mild stimulant effects that enable workers to stave off fatigue. Moderate to high doses (5-15 g) are reported to have opioid-like effects. At these doses, kratom has been used for the management of pain, diarrhea, and opioid withdrawal symptoms, as well as for its properties as a euphoriant. Very high doses (>15 g) of kratom tend to be quite sedating and can induce stupor, mimicking opioid effects... .. Most of the opioid-like activity of kratom has been attributed to the presence of the indole alkaloids, mitragynine and 7-hydroxymitragynine. Both compounds have been shown to have analgesic and antinociceptive effects in animals, although 7-hydroxymitragynine is more potent... in Southeast Asia, it has long been recognized that individuals will seek out and abuse kratom for its euphoric and mind-altering effects and that chronic users can become tolerant of, physically dependent on, and addicted to kratom. Kratom addiction is considered such a problem that many Southeast Asian countries have outlawed the use of kratom." | involves ingestion of the plant’s raw leaves or consumption of teas that are brewed or steeped from the leaves. Kratom leaves are used for their complex, dose-dependent pharmacologic effects. Low to moderate doses (1-5 g) of the leaves reportedly produce mild stimulant effects that enable workers to stave off fatigue. Moderate to high doses (5-15 g) are reported to have opioid-like effects. At these doses, kratom has been used for the management of pain, diarrhea, and opioid withdrawal symptoms, as well as for its properties as a euphoriant. Very high doses (>15 g) of kratom tend to be quite sedating and can induce stupor, mimicking opioid effects... .. Most of the opioid-like activity of kratom has been attributed to the presence of the indole alkaloids, mitragynine and 7-hydroxymitragynine. Both compounds have been shown to have analgesic and antinociceptive effects in animals, although 7-hydroxymitragynine is more potent... in Southeast Asia, it has long been recognized that individuals will seek out and abuse kratom for its euphoric and mind-altering effects and that chronic users can become tolerant of, physically dependent on, and addicted to kratom. Kratom addiction is considered such a problem that many Southeast Asian countries have outlawed the use of kratom." | ||
| [Pharmacology of kratom: an emerging botanical agent with stimulant, analgesic and opioid-like effects., Prozialeck, W.C., Jivan, J.K., Andurkar, S.V., The Journal of the American Osteopathic Association, | [Pharmacology of kratom: an emerging botanical agent with stimulant, analgesic and opioid-like effects., Prozialeck, W.C., Jivan, J.K., Andurkar, S.V., The Journal of the American Osteopathic Association, | ||
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| + | "The clinical effects of Kratom are dose-dependent. At low doses, Kratom produces a stimulant effect; at higher doses, the opioid effect predominates... M. speciosa Korth is a plant made up of more than 25 alkaloids that vary in specific composition depending on the plant' | ||
| + | [Rosenbaum, Christopher D., Stephanie P. Carreiro, and Kavita M. Babu. "Here today, gone tomorrow… and back again? A review of herbal marijuana alternatives (K2, Spice), synthetic cathinones (bath salts), kratom, Salvia divinorum, methoxetamine, | ||
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| + | Mitragyna speciosa, Korthals, P.W., Kruidkunde [Verhandelingen over de natuurlijke geschiedenis der Nederlandsche overzeesche bezittingen; | ||
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mitragyna_speciosa_korth.1438505967.txt.gz · Zuletzt geändert: 2015/08/02 08:59 von andreas