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Chilean Laurel, **Chilenischer Lorbeer** | Chilean Laurel, **Chilenischer Lorbeer** |
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Evergreen tree, native to Chile, Argentina. | Evergreen tree native to Chile, Argentina. |
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"The leaves of Laurelia sempervirens (Monimiaceae), an endemic Chilean tree known as ‘Laurel’, were used by the Mapuche Amerindians for treating headache and as a diuretic. Intravenous administration of a hydroalcoholic L. sempervirens extract to rats, elicited a hypotensive response of −27.0%±2.0% in the mean blood pressure of normotensive animals at a dose of 5 mg crude extract ± kg body weight. Bioassay-guided isolation of the active ‘Laurel’ metabolites led to the alkaloid laurotetanine as the main hypotensive principle of L. sempervirens leaves." \\ | "The leaves of Laurelia sempervirens (Monimiaceae), an endemic Chilean tree known as ‘Laurel’, were used by the Mapuche Amerindians for treating headache and as a diuretic. Intravenous administration of a hydroalcoholic L. sempervirens extract to rats, elicited a hypotensive response of −27.0%±2.0% in the mean blood pressure of normotensive animals at a dose of 5 mg crude extract ± kg body weight. Bioassay-guided isolation of the active ‘Laurel’ metabolites led to the alkaloid [[https://www.rsc.org/Merck-Index/monograph/mono1500005443/laurotetanine?q=unauthorize|laurotetanine]] as the main hypotensive principle of L. sempervirens leaves." \\ |
[ Hypotensive effect of Laurelia sempervirens (Monimiaceae) on normotensive rats. Schmeda‐Hirschmann, G., Loyola, J. I., Rodríguez, J., & Dutra‐Behrens, M., Phytotherapy Research, Vol.8(1), 1994, 49-51] | [ Hypotensive effect of Laurelia sempervirens (Monimiaceae) on normotensive rats. Schmeda‐Hirschmann, G., Loyola, J. I., Rodríguez, J., & Dutra‐Behrens, M., Phytotherapy Research, Vol.8(1), 1994, 49-51] |
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