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--- laurelia_sempervirens_ruiz_pav._tul [2014/09/10 21:11] – angelegt andreas
+++ laurelia_sempervirens_ruiz_pav._tul [2015/06/13 09:39] (aktuell) – Externe Bearbeitung 127.0.0.1
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 Chilean Laurel, **Chilenischer Lorbeer**
-Evergreen tree, native to Chile, Argentina.
+Evergreen tree native to Chile, Argentina.
-"The leaves of Laurelia sempervirens (Monimiaceae), an endemic Chilean tree known as ‘Laurel’, were used by the Mapuche Amerindians for treating headache and as a diuretic. Intravenous administration of a hydroalcoholic L. sempervirens extract to rats, elicited a hypotensive response of −27.0%±2.0% in the mean blood pressure of normotensive animals at a dose of 5 mg crude extract ± kg body weight. Bioassay-guided isolation of the active ‘Laurel’ metabolites led to the alkaloid laurotetanine as the main hypotensive principle of L. sempervirens leaves." \\
+"The leaves of Laurelia sempervirens (Monimiaceae), an endemic Chilean tree known as ‘Laurel’, were used by the Mapuche Amerindians for treating headache and as a diuretic. Intravenous administration of a hydroalcoholic L. sempervirens extract to rats, elicited a hypotensive response of −27.0%±2.0% in the mean blood pressure of normotensive animals at a dose of 5 mg crude extract ± kg body weight. Bioassay-guided isolation of the active ‘Laurel’ metabolites led to the alkaloid [[https://www.rsc.org/Merck-Index/monograph/mono1500005443/laurotetanine?q=unauthorize|laurotetanine]] as the main hypotensive principle of L. sempervirens leaves." \\
 [ Hypotensive effect of Laurelia sempervirens (Monimiaceae) on normotensive rats. Schmeda‐Hirschmann, G., Loyola, J. I., Rodríguez, J., & Dutra‐Behrens, M., Phytotherapy Research, Vol.8(1), 1994, 49-51]
+Hydrodistillation of L. sempervirens leaves and bark yields 2.79% and 6.26% essential oil, respectively. The main constituents in the leaf oil were safrole (82.41 %) and limonene. "Safrole was also the main constituent in oil from bark (49.71%), and methyl eugenol (18.04%) was the second main constituent, followed by limonene." \\
+[Bioactivity of essential oils from leaves and bark of Laurelia sempervirens and Drimys winteri against Acyrthosiphon pisum. Zapata, N., Lognay, G., & Smagghe, G., Pest management science, Vol.66(12), 2010, 1324-1331]