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Vorhergehende Überarbeitung
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xysmalobium_undulatum_l._r.br [2015/10/14 12:13]
andreas |
xysmalobium_undulatum_l._r.br [2015/10/14 12:23]
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| "The root of Xysmalobium undulatum (L.) R. Br. (Asclepiadaceae) is traditionally used for numerous purposes, e.g. treatment of hysteria in young women and headache relief, whereas in Germany an alcoholic-aqueous root extract (Uzara®) is marketed for treatment of diarrhoea... root extracts and aerial part extracts of X. undulatum and the Uzara® commercial product... showed in vitro affinity for the SSRI binding site in rat brain in a radioligand assay... However, a bioassay guided isolation of the Uzara® commercial product showed no fraction with specific activity." \\ | "The root of Xysmalobium undulatum (L.) R. Br. (Asclepiadaceae) is traditionally used for numerous purposes, e.g. treatment of hysteria in young women and headache relief, whereas in Germany an alcoholic-aqueous root extract (Uzara®) is marketed for treatment of diarrhoea... root extracts and aerial part extracts of X. undulatum and the Uzara® commercial product... showed in vitro affinity for the SSRI binding site in rat brain in a radioligand assay... However, a bioassay guided isolation of the Uzara® commercial product showed no fraction with specific activity." \\ |
| [Pharmacological Studies on Xysmalobium undulatum and Mondia whitei – Two South African plants with in vitro SSRI activity. ME Pedersen, A Weng, A Sert, GI Stafford, J van Staden, M Nielsen, AK Jäger, Planta Med 2006; 72 - P_123] | [Pharmacological Studies on Xysmalobium undulatum and Mondia whitei - Two South African plants with in vitro SSRI activity. ME Pedersen, A Weng, A Sert, GI Stafford, J van Staden, M Nielsen, AK Jäger, Planta Med 2006; 72 - P_123] |
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| "Limited scientific studies on the biological activity of uzara have been done. In vitro antisecretory antidiarrhoeal action was confirmed. Central nervous system activity was conflicting, in vitro and in vivo (animals) studies were inconclusive and no clinical studies have been performed. No antimutagenic effects have been reported and no toxicity up to date has been associated with uzara consumption. Significant cross-reactivity of uzara compounds with commercial digoxin and digitoxin assays may interfere with therapeutic drug monitoring." \\ | "Limited scientific studies on the biological activity of uzara have been done. In vitro antisecretory antidiarrhoeal action was confirmed. Central nervous system activity was conflicting, in vitro and in vivo (animals) studies were inconclusive and no clinical studies have been performed. No antimutagenic effects have been reported and no toxicity up to date has been associated with uzara consumption. Significant cross-reactivity of uzara compounds with commercial digoxin and digitoxin assays may interfere with therapeutic drug monitoring." \\ |
| [Xysmalobium undulatum (uzara)–review of an antidiarrhoeal traditional medicine., Vermaak, I., Enslin, G.M., Idowu, T.O., Viljoen, A.M., Journal of ethnopharmacology, 156, 2014, 135-146] | [Xysmalobium undulatum (uzara)-review of an antidiarrhoeal traditional medicine., Vermaak, I., Enslin, G.M., Idowu, T.O., Viljoen, A.M., Journal of ethnopharmacology, 156, 2014, 135-146] |
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