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--- xysmalobium_undulatum_l._r.br [2014/07/04 16:37]
andreas angelegt
+++ xysmalobium_undulatum_l._r.br [2015/06/13 11:41]
127.0.0.1 Externe Bearbeitung
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 "The South African Xhosa people for many generations used the root as remedy (Uzara). African healers use the Uzara Medicine to threat indigestion, painful menstruation, migraine and colds. In Germany, a dry extract is obtained since 1911 from the Uzara root to threat diarrhea." [[http://de.wikipedia.org/wiki/Uzara]]
+"The root of Xysmalobium undulatum (L.) R. Br. (Asclepiadaceae) is traditionally used for numerous purposes, e.g. treatment of hysteria in young women and headache relief, whereas in Germany an alcoholic-aqueous root extract (Uzara®) is marketed for treatment of diarrhoea...  root extracts and aerial part extracts of X. undulatum and the Uzara® commercial product... showed in vitro affinity for the SSRI binding site in rat brain in a radioligand assay... However, a bioassay guided isolation of the Uzara® commercial product showed no fraction with specific activity." [Pharmacological Studies on Xysmalobium undulatum and Mondia whitei – Two South African plants with in vitro SSRI activity. ME Pedersen, A Weng, A Sert, GI Stafford, J van Staden, M Nielsen, AK Jäger, Planta Med 2006; 72 - P_123]

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