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Beide Seiten der vorigen Revision Vorhergehende Überarbeitung Nächste Überarbeitung | Vorhergehende Überarbeitung Nächste Überarbeitung Beide Seiten der Revision | ||
sanguinaria_canadensis_l [2015/10/23 15:50] andreas |
sanguinaria_canadensis_l [2015/10/23 20:06] andreas |
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"In isolated, isometrically contracting left guinea pig atria, sanguinarine, | "In isolated, isometrically contracting left guinea pig atria, sanguinarine, | ||
[Sanguinarine: | [Sanguinarine: | ||
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+ | "The sanguinaria regimen reduced plaque by 57%, gingival inflammation by 60%, and sulcular bleeding by 45% from baseline compared with placebo group reductions of 27% (plaque) and 21% (gingival inflammation), | ||
+ | [Long-term clinical evaluation of toothpaste and oral rinse containing sanguinaria extract in controlling plaque, gingival inflammation, | ||
"The rhizome extracts, as well as a methanol extract of S. canadensis suspension-cell cultures inhibited the growth of H. pylori in vitro, with a MIC50 range of 12.5–50.0 µg/ml. Three isoquinoline alkaloids were identified in the active fraction. Sanguinarine and chelerythrine, | "The rhizome extracts, as well as a methanol extract of S. canadensis suspension-cell cultures inhibited the growth of H. pylori in vitro, with a MIC50 range of 12.5–50.0 µg/ml. Three isoquinoline alkaloids were identified in the active fraction. Sanguinarine and chelerythrine, | ||
- | [In vitro susceptibility of Helicobacter pylori to isoquinoline alkaloids from Sanguinaria canadensis and Hydrastis canadensis., | + | [In vitro susceptibility of Helicobacter pylori to isoquinoline alkaloids from Sanguinaria canadensis and Hydrastis canadensis., |
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+ | The dried rhizome, with roots removed (Sanguinariae canadensis rhizoma), is traditionally used (infusion) as an emetic, expectorant and spasmolytic to treat bronchitis, asthma, cough, croup, laryngitis and pharyngitis. Most common modern use is (as extract in mouth rinses and toothpaste) to conteract dental plaque and gingivitis. \\ | ||
+ | [Medicinal Plants of the World. Ben-Erik Van Wyk and Michael Wink, Pretoria 2004, 286] | ||
+ | Sanguinarine has recently been shown to exhibit potent anti-MRSA activity in vitro by disrupting the cytoplasmic membrane of MRSA. "The activity of sanguinarine against MRSA strains ranged from 3.12 to 6.25 µg/ml, while the minimum inhibitory concentrations of the two reference strains are 3.12 µg/ml and 1.56 µg/ml. The treatment of the cells with sanguinarine induced the release of membrane-bound cell wall autolytic enzymes, which eventually resulted in lysis of the cell." \\ | ||
+ | [The mechanism of action of sanguinarine against methicillin-resistant Staphylococcus aureus., Obiang-Obounou, | ||
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Millspaugh, | Millspaugh, | ||
[[http:// | [[http:// |