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--- sanguinaria_canadensis_l [2015/10/23 09:29]
andreas
+++ sanguinaria_canadensis_l [2015/10/23 15:46]
andreas
@@ Zeile 5: / Zeile 5: @@
 "Although bloodroot is an ingredient of some compound cough remedies, it contains the poisonous alkaloid sanguinarine, and the U.S. Food and Drug Administration has characterized Sanguinaria canadensis as an unsafe herb (J. A. Duke 1985). Native Americans used it medicinally to treat ulcers and sores, croup, cramps, burns, tapeworms, fevers, diarrhea, and irregular periods, in cough syrups, as a spring emetic and blood purifier, to stop vomiting, and as a love charm, as well as in cermonial face paint (D. E. Moerman 1986)." \\
 [[http://www.efloras.org/florataxon.aspx?flora_id=1&taxon_id=220011939]]
+"The rhizome extracts, as well as a methanol extract of S. canadensis suspension-cell cultures inhibited the growth of H. pylori in vitro, with a MIC50 range of 12.5–50.0 µg/ml. Three isoquinoline alkaloids were identiﬁed in the active fraction. Sanguinarine and chelerythrine, two benzophenanthridine alkaloids, inhibited the growth of the bacterium, with an MIC50 of 50.0 and 100.0 µg/ml, respectively." \\
+[In vitro susceptibility of Helicobacter pylori to isoquinoline alkaloids from Sanguinaria canadensis and Hydrastis canadensis., Mahady, G.B., Pendland, S.L., Stoia, A., Chadwick, L.R., Phytotherapy Research, 17(3), 20003, 217-221]

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